SH2D1A Products

Antibodies
SH2D1A Antibody (1C9)
SH2D1A Antibody (1C9)
H00004068-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
SH2D1A Antibody (782702)
SH2D1A Antibody (782702)
MAB7440
Species: Hu
Applications: WB
Host: Mouse Monoclonal
SH2D1A Antibody
SH2D1A Antibody
AF7440
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Lysates
SH2D1A Overexpression Lysate ...
SH2D1A Overexpression Lysate (Dena...
H00004068-T01
Species: Hu
Applications: WB
SH2D1A Overexpression Lysate ...
SH2D1A Overexpression Lysate (Native)
NBL1-15918
Applications: WB
Proteins
SH2D1A Recombinant Protein
SH2D1A Recombinant Protein
NBP1-50869
Applications: PAGE
RNAi
SH2D1A RNAi
SH2D1A RNAi
H00004068-R01
Species: Hu

Description

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 4068
Alternate Names
  • T cell signal transduction molecule SAP
  • T-cell signal transduction molecule SAP
  • SLAM associated protein/SH2 domain protein 1A
  • SLAM-associated protein
  • signaling lymphocyte activation molecule-associated protein
  • Duncan disease SH2-protein
  • SH2 domain-containing protein 1A
  • Signaling lymphocytic activation molecule-associated protein
  • SAP/SH2D1A
  • MTCP1
  • FLJ92177
  • EBVS
  • XLPDFLJ18687
  • XLPSH2 domain protein 1A
  • SAPlymphoproliferative syndrome
  • DSHPLYP
  • IMD5
  • SH2 domain containing 1A

Research Areas for SH2D1A

Find related products by research area and learn more about each of the different research areas below.

Immune System Diseases
Immunology

PTMs for SH2D1A

Learn more about PTMs related to SH2D1A.

Phosphorylation
Methylation
Cleavage
Dephosphorylation

Bioinformatics Tool for SH2D1A

Discover related pathways, diseases and genes to SH2D1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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