Independent Antibodies: Western Blot: SF3A1 Antibody [NB100-79843] - Detection of Human SF3a120/SAP114 on HeLa whole cell lysate using NB100-79843. SF3a120/SAP114 was also IPed by rabbit anti-SF3a120/SAP114 ...read more
Immunocytochemistry/ Immunofluorescence: SF3A1 Antibody [NB100-79843] - Detection of Human SF3a120/SAP114 by IHC-IF. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-SF3a120/SAP114 ...read more
Immunohistochemistry-Paraffin: SF3A1 Antibody [NB100-79843] - Detection of Human SF3a120/SAP114 by Immunohistochemistry. Sample: FFPE section of human pancreatic islet cell tumor. Antibody: Affinity purified rabbit ...read more
Immunohistochemistry-Paraffin: SF3A1 Antibody [NB100-79843] - FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti- SF3a120/SAP114 used at a dilution of 1:100. Detection: DAB staining using ...read more
Immunohistochemistry: SF3A1 Antibody [NB100-79843] - Sample: FFPE sections of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti- SF3a120/SAP114 used at a dilution of 1:200 ...read more
This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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