SF3A1 Products

Antibodies
SF3A1 Antibody
SF3A1 Antibody
NB100-79843
Species: Hu, Mu, Bovine, Canine, Equine, Ferret, Primate, Rabbit, Rhesus Macaque
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SF3A1 Antibody
SF3A1 Antibody
NBP1-87214
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SF3A1 Antibody (3F4)
SF3A1 Antibody (3F4)
NBP2-45803
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Lysates
SF3A1 Overexpression Lysate ( ...
SF3A1 Overexpression Lysate (Native)
NBL1-15874
Applications: WB
Proteins
SF3A1 Partial Recombinant Pro ...
SF3A1 Partial Recombinant Protein
H00010291-Q01
Species: Hu
Applications: WB, ELISA, PA
SF3A1 Recombinant Protein
SF3A1 Recombinant Protein
H00010291-P01
Species: Hu
Applications: WB, ELISA, PA
SF3A1 Recombinant Protein Ant ...
SF3A1 Recombinant Protein Antigen
NBP1-87215PEP
Species: Hu
Applications: AC
RNAi
SF3A1 RNAi
SF3A1 RNAi
H00010291-R01
Species: Hu
Applications: RNAi, RNAi SP
SF3A1 RNAi
SF3A1 RNAi
H00010291-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

SF3A1 encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 10291
Alternate Names
  • SF3A120
  • splicing factor 3A subunit 1
  • PRP21
  • splicing factor 3 subunit 1
  • SAP 114
  • spliceosome associated protein 114
  • Spliceosome-associated protein 114
  • pre-mRNA splicing factor SF3a (120 kDa subunit)
  • SF3a120
  • pre-mRNA processing 21
  • PRPF21
  • SAP114splicing factor 3a, subunit 1, 120kD
  • Prp21
  • splicing factor 3a, subunit 1, 120kDa

Bioinformatics Tool for SF3A1

Discover related pathways, diseases and genes to SF3A1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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