SESN3 Antibody (2C9) - Azide and BSA Free

Western Blot: SESN3 Antibody (2C9) [H00143686-M02] - SESN3 monoclonal antibody (M02), clone 2C9. Analysis of SESN3 expression in human pancreas.

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clone: 2C9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

SESN3 Antibody (2C9) - Azide and BSA Free Summary

• Immunogen: SESN3 (AAH17296, 212 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. INPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSGAFLHFFAF
• Specificity: SESN3 (2C9)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SESN3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SESN3 Antibody (2C9) - Azide and BSA Free

• SEST3MGC29667
• sestrin 3
• sestrin-3

Background

Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SESN3 Antibody (H00143686-M02)(2)

Publications using H00143686-M02

• Pengfei L, Huina L, Yongkai W et al. E2F transcription factor 1 is involved in the phenotypic modulation of esophageal squamous cell carcinoma cells via microRNA-375. Bioengineered. 2021-12-15 [PMID: 34699320]
• Hwang I, Oh H, Santo E et al. FOXO protects against age-progressive axonal degeneration. Aging Cell 2017-11-26 [PMID: 29178390]

Bioinformatics

• Gene Symbol: SESN3
• Entrez:
  • 143686(Human)
• OMIM:
  • 607768(Human)
• Uniprot:
  • AAH17296(Human)