Hu, Mu, Rt, Pm, RMApplications:
WB, ICC/IF, IHC, IHC-PHost:
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.
Research Areas for SESN3
Find related products by research area and learn more about each of the different research areas below.Cell Cycle and Replication
Bioinformatics Tool for SESN3
Discover related pathways, diseases and genes to SESN3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.