Species: Hu, Mu, Rt, Pm, RM
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu, Mu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
143686 |
| Alternate Names |
- SEST3MGC29667
- sestrin 3
- sestrin-3
|
Research Areas for SESN3
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
