Serpin A3/alpha 1-Antichymotrypsin Antibody - BSA Free

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody [NBP1-90296] - Staining of human cerebral cortex, cervix, uterine, colon and liver using Anti-SERPINA3 antibody NBP1-90296 (A) shows similar protein distribution across tissues to independent antibody NBP1-90295 (B).

Staining of human cerebral cortex using Anti-SERPINA3 antibody NBP1-90296.

Staining of human cervix, uterine using Anti-SERPINA3 antibody NBP1-90296.

Staining of human liver using Anti-SERPINA3 antibody NBP1-90296.

Staining of human colon using Anti-SERPINA3 antibody NBP1-90296.

Analysis in human cell line RT-4 and human cell line U-251 MG.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Serpin A3/alpha 1-Antichymotrypsin Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Serpin A3/alpha 1-Antichymotrypsin Antibody - BSA Free (NBP1-90296) is a polyclonal antibody validated for use in IHC and WB. Anti-Serpin A3/alpha 1-Antichymotrypsin Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGGAPHR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SERPINA3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Serpin A3/alpha 1-Antichymotrypsin Protein (NBP1-90296PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Serpin A3/alpha 1-Antichymotrypsin Antibody - BSA Free

• AACTMGC88254
• ACTGIG25
• alpha 1-Antichymotrypsin
• alpha-1-antichymotrypsin
• antitrypsin), member 3
• Cell growth-inhibiting gene 24/25 protein
• growth-inhibiting protein 24
• growth-inhibiting protein 25
• member 3
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• serine (or cysteine) proteinase inhibitor, clade A, member 3
• Serpin A3
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Background

Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Serpin A3/alpha 1-Antichymotrypsin Antibody (NBP1-90296)(2)

Publications using NBP1-90296

• Bachmann J, Burte F, Pramana S et al. Affinity Proteomics Reveals Elevated Muscle Proteins in Plasma of Children with Cerebral Malaria. PLoS Pathog 2014-04-01 [PMID: 24743550]
• Haggmark A, Bystrom S, Ayoglu B et al. Antibody-based profiling of cerebrospinal fluid within multiple sclerosis. Proteomics 2013-08-01 [PMID: 23696371]

Bioinformatics

• Gene Symbol: SERPINA3