Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) - BSA Free

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Analysis in human liver and skeletal muscle tissues using NBP3-07987 antibody. Corresponding Serpin A3/alpha 1-Antichymotrypsin RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human cerebral cortex shows cytoplasmic and nuclear positivity in a subset of glial cells.

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) [NBP3-07987] - Staining of human uterine cervix shows moderate cytoplasmic positivity in squamous epithelial cells.

• Reactivity: Hu
• Applications: IHC
• Clone: CL10697
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) - BSA Free Summary

• Description: Novus Biologicals Mouse Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) - BSA Free (NBP3-07987) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from P01011, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.2, containing 40% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Serpin A3/alpha 1-Antichymotrypsin Antibody (CL10697) - BSA Free

• AACTMGC88254
• ACTGIG25
• alpha 1-Antichymotrypsin
• alpha-1-antichymotrypsin
• antitrypsin), member 3
• Cell growth-inhibiting gene 24/25 protein
• growth-inhibiting protein 24
• growth-inhibiting protein 25
• member 3
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• serine (or cysteine) proteinase inhibitor, clade A, member 3
• Serpin A3
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Background

Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINA3