SENP3 Antibody [Janelia Fluor® 525]

• Reactivity: Hu, Mu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 525

SENP3 Antibody [Janelia Fluor® 525] Summary

• Immunogen: The immunogen for this product maps to a region between residue 1 and 50 of human SUMO1/Sentrin/SMT3 Specific Peptidase 3 using the numbering given in entry NP_056485.2 (GeneID 26168).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SENP3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SENP3 Antibody [Janelia Fluor® 525]

• DKFZP586K0919
• DKFZp762A152
• EC 3.4.22
• EC 3.4.22.-
• sentrin/SUMO-specific protease 3
• Sentrin/SUMO-specific protease SENP3
• sentrin-specific protease 3
• SMT3IP1
• SSP3DKFZp586K0919
• SUMO1/sentrin/SMT3 specific peptidase 3
• SUMO1/sentrin/SMT3 specific protease 3
• SUMO-1-specific protease 3
• SUSP3

Background

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 (PubMed 16738315)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SENP3