SENP3 Products

Description

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 (PubMed 16738315)).(supplied by OMIM)

Bioinformatics

Entrez	26168 Human 80886 Mouse
Uniprot	NM_015670 Human NP_056485 Human NP_056485.2 Human Q9H4L4 Human
Product By Gene ID	26168
Alternate Names	DKFZP586K0919 DKFZp762A152 EC 3.4.22 EC 3.4.22.- sentrin/SUMO-specific protease 3 Sentrin/SUMO-specific protease SENP3 sentrin-specific protease 3 SMT3IP1 SSP3DKFZp586K0919 SUMO1/sentrin/SMT3 specific peptidase 3 SUMO1/sentrin/SMT3 specific protease 3 SUMO-1-specific protease 3 SUSP3