PELP1 Antibody


Western Blot: PELP1 Antibody [NB200-331] - Detection of mouse PELP1/MNAR by western blot. Samples: Whole cell lysate (50 ug) from NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit more
Immunohistochemistry-Paraffin: PELP1 Antibody [NB200-331] - Human ovarian carcinoma.~ Antibodies: Affinity purified rabbit anti-PELP1/MNAR used at a dilution of 1:2,500 (0.4ug/ml) (left) used at a dilution of 1:5,000 more
Biological Strategies: Western Blot: PELP1 Antibody [NB200-331] - Detection of Human PELP1/MNAR by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. more
Immunohistochemistry-Paraffin: PELP1 Antibody [NB200-331] - Samples: FFPE sections of mouse renal cell carcinoma.~ Antibodies: Affinity purified rabbit anti-PELP1/MNAR dilution of 1:2,500 (0.4ug/ml) (left) and used at more
Independent Antibodies: Immunoprecipitation: PELP1 Antibody [NB200-331] - Detection of human PELP1/MNAR by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP more

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P, IP
1.0 mg/ml

Order Details

PELP1 Antibody Summary

A synthetic peptide mapping to a region between residues 1000 and 1050 of human, proline-, glutamic acid-, leucine-rich protein 1/ modulator of nongenomic activity of estrogen receptor using the numbering given in entry AAN41255.1 (GeneID 27043).
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunohistochemistry 1:2000 - 1:10000
  • Immunohistochemistry-Paraffin 1:2000 - 1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2500-1:10000
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
HeLa Nuclear Cell Lysate
Read Publications using
NB200-331 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
0.09% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for PELP1 Antibody

  • HMX3
  • MNARmodulator of nongenomic activity of estrogen receptor
  • Modulator of non-genomic activity of estrogen receptor
  • P160
  • proline and glutamic acid rich nuclear protein
  • proline, glutamate and leucine rich protein 1
  • proline, glutamic acid and leucine rich protein 1
  • proline-, glutamic acid- and leucine-rich protein 1
  • proline-, glutamic acid-, leucine-rich protein 1
  • Transcription factor HMX3


PELP1 is a coactivator of estrogen receptor (see ESR1; MIM 133430)-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors (Choi et al., 2004).[supplied by OMIM]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PELP1 Antibody (NB200-331)(18)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

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Showing Publications 1 - 10 of 18. Show All 18 Publications.
Publications using NB200-331 Applications Species
Regan Anderson TM, Ma SH, Raj GV et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer Cancer Res. Jan 29 2016 [PMID: 26825173] (WB, Human) WB Human
Cortez V, Mann M, Tekmal S et al. Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer. Breast Cancer Res 2012 Jul [PMID: 22812534]
Chakravarty D, Roy SS, Babu CR et al. Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis. Clin Cancer Res 2011 Apr [PMID: 21421858]
Nair BC, Nair SS, Chakravarty D et al. Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1. Cancer Res 2010 Sep [PMID: 20807815]
Kayahara M, Ohanian J, Ohanian V et al. MNAR functionally interacts with both NH2- and COOH-terminal GR domains to modulate transactivation. Am J Physiol Endocrinol Metab 2008 Nov [PMID: 18682536]
Dimple C, Nair SS, Rajhans R et al. Role of PELP1/MNAR signaling in ovarian tumorigenesis. Cancer Res 2008 Jun [PMID: 18559538]
Nagpal JK, Nair S, Chakravarty D et al. Growth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathway. Mol Cancer Res 2008 May [PMID: 18505929]
Galluzzo P, Ascenzi P, Bulzomi P et al. The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation. Endocrinology 2008 May [PMID: 18239068]
Rajhans R, Nair HB, Nair SS et al. Modulation of in situ estrogen synthesis by proline-, glutamic acid-, and leucine-rich protein-1: potential estrogen receptor autocrine signaling loop in breast cancer cells. Mol Endocrinol 2008 Mar [PMID: 18079323]
Ohshiro K, Rayala SK, Kondo S et al. Identifying the estrogen receptor coactivator PELP1 in autophagosomes. Cancer Res 2007 Sep [PMID: 17804729]
Show All 18 Publications.

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Gene Symbol PELP1