SENP3 Antibody [Alexa Fluor® 647]

• Reactivity: Hu, Mu
• Applications: IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 647

SENP3 Antibody [Alexa Fluor® 647] Summary

• Immunogen: The immunogen for this product maps to a region between residue 1 and 50 of human SUMO1/Sentrin/SMT3 Specific Peptidase 3 using the numbering given in entry NP_056485.2 (GeneID 26168).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SENP3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SENP3 Antibody [Alexa Fluor® 647]

• DKFZP586K0919
• DKFZp762A152
• EC 3.4.22
• EC 3.4.22.-
• sentrin/SUMO-specific protease 3
• Sentrin/SUMO-specific protease SENP3
• sentrin-specific protease 3
• SMT3IP1
• SSP3DKFZp586K0919
• SUMO1/sentrin/SMT3 specific peptidase 3
• SUMO1/sentrin/SMT3 specific protease 3
• SUMO-1-specific protease 3
• SUSP3

Background

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 (PubMed 16738315)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SENP3