SASH1 Antibody [DyLight 755]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 755

SASH1 Antibody [DyLight 755] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human SAM and SH3 domain containing 1 (NP_056093.3).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SASH1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23235829).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SASH1 Antibody [DyLight 755]

• dJ323M4
• dJ323M4.1
• KIAA0790RP3-323M4.1
• PEPE1
• Proline-glutamate repeat-containing protein
• SAM and SH3 domain containing 1,2500002E12Rik
• SAM and SH3 domain-containing protein 1
• SH3D6A

Background

SASH1 (SAM and SH3 domain containing 1) was identified in an in silico analysis of loss of heterozygosity (LOH) to identify genes downregulated in breast cancer. Since this discovery, it has also been found to be a candidate tumor suppressor in colon cancer. Structurally, SASH1 contains two SAM (sterile alpha motif) domains and one SH3 domain indicating a role in signal transduction and as a signaling adapter.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SASH1