S100A1 Antibody Pair [HRP]

Sandwich ELISA: S100A1 Antibody Pair [HRP] [NBP2-79557] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

• Reactivity: Mu
• Applications: ELISA
• Conjugate: HRP
• Standard Curve Range: 31.25-2000 pg/ml (example only; lot dependent)
• Sensitivity: 31.25 pg/ml (example only; lot dependent)

S100A1 Antibody Pair [HRP] Summary

• Description: Solid Phase sandwich ELISA for the quantitative determination of Mouse S100A1.
• Additional Information: Recombinant Monoclonal Antibody
• Specificity: This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Mouse S100A1.
• Source: HEK293
• Standard Curve Range: 31.25-2000 pg/ml (example only; lot dependent)
• Sensitivity: 31.25 pg/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 ul
• Gene: S100A1

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for S100A1 Antibody Pair [HRP]

• protein S100-A1
• S100 alpha
• S100 calcium binding protein A1
• S100 calcium-binding protein A1S100
• S-100 protein alpha chain
• S-100 protein subunit alpha
• S100 protein, alpha polypeptide
• S100A
• S100A1
• S100-alpha

Background

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: S100A1