S100A1 Products

Description

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.

Bioinformatics

Entrez	20193 Mouse 295214 Rat 528735 Bovine 6271 Human
Uniprot	P02639 Bovine P23297 Human
Product By Gene ID	6271
Alternate Names	protein S100-A1 S100 alpha S100 calcium binding protein A1 S100 calcium-binding protein A1S100 S-100 protein alpha chain S-100 protein subunit alpha S100 protein, alpha polypeptide S100A S100-alpha

Research Areas for S100A1

Find related products by research area and learn more about each of the different research areas below.

Astrocyte Markers
Breast Cancer
Cancer
Cell Biology
Cellular Markers
Cytoskeleton Markers
Hypoxia
Lipid and Metabolism
Neuronal Cell Markers
Neuroscience
Peroxisome Markers
Signal Transduction