PTPRK Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: PTPRK Antibody [NBP2-58338] - Staining of human cell line MCF7 shows localization to cell junctions. Antibody staining is shown in green.

• Reactivity: Hu
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PTPRK Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PTPRK Antibody - BSA Free (NBP2-58338) is a polyclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTM
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTPRK
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  PTPRK Recombinant Protein Antigen (NBP2-58338PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PTPRK Antibody - BSA Free

• DKFZp686C2268
• DKFZp779N1045
• EC 3.1.3.48
• protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa
• protein tyrosine phosphatase, receptor type, K
• Protein-tyrosine phosphatase kappa
• protein-tyrosine phosphatase, receptor type, kappa
• PTPK
• receptor type, K (R-PTP-KAPPA
• receptor-type tyrosine-protein phosphatase kappa

Background

PTP kappa (PTPRK)is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP kappa is c-transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins and, at the primary sequence level, share little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP kappa is involved in the regulation of processes involving cell contact and adhesion, tumour invasion and metastasis. Regulation of processes involving cell contact and adhesion such as growth control. tumor invasion. and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTP-kappa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPRK