Progesterone R/NR3C3 Antibody (A9621A) [Unconjugated]

• Reactivity: Hu
• Applications: WB, IHC, IP, ELISA
• Clone: A9621A
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Suitable Sample Type: 23005

Progesterone R/NR3C3 Antibody (A9621A) [Unconjugated] Summary

• Immunogen: Recombinant human Progesterone R/NR3C3 Isoform A
  aa 166-263
• Specificity: This antibody specifically recognizes human PR isoform A and B and cross reacts with mouse and rat PR isoform A and B. Not yet tested in other species.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PGR
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

• Storage: This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Progesterone R/NR3C3 Antibody (A9621A) [Unconjugated]

• NR3C3
• NR3C3PRNuclear receptor subfamily 3 group C member 3
• PGR
• Progesterone R
• progesterone receptor
• ProgesteroneR

Background

Progesterone receptor (PR; NR3C3) is a member of the Steroid Receptor family. PR binds progesterone. PR is expressed in the uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Progesterone R/NR3C3 Antibody (PP-A9621A-00)(2)

Publications using PP-A9621A-00

• José M Pingarrón Disposable Amperometric Immunosensor for the Determination of Human P53 Protein in Cell Lysates Using Magnetic Micro-Carriers Biosensors (Basel), 2016;6(4):. 2016 [PMID: 27879639] (SDS-PAGE)
• Wang J, Dicken C, Lustbader JW, Tortoriello DV Evidence for a Mullerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertil. Steril., 2009;91(4):1195-203. 2009 [PMID: 18328480] (ICC, Human)

FAQs for Progesterone R/NR3C3 Antibody (PP-A9621A-00). (Showing 1 - 1 of 1 FAQs).

1. I am interested in getting antibodies for PR (progesterone receptor) that would work in flow cytometry. Could you recommend some choices?
   • We do not currently have any antibodies directed towards the progesterone receptor that have been validated in flow cytometry, but any of our antibodies that work in ICC should work just fine in flow as they are essentially the same application. Please see this link for our Progesterone Receptor antibodies validated in ICC.

Bioinformatics

• Gene Symbol: PGR