Profilin 2 Antibody

Western Blot: Profilin 2 Antibody[NB120-14251]-E coli-derived fusion protein as test antigen. Affi-anti-PFN2 IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Product Discontinued

Profilin 2 Antibody Summary

• Immunogen: Fusion protein
• Localization: Cytoskeleton
• Specificity: Profilin 2
• Clonality: Polyclonal
• Host: Chicken
• Gene: PFN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000
• Application Notes: In Western Blot the predicted molecular weight: 17 kDa.

Reactivity Notes

Cross-reacts with Human, Mouse and Rat.Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for Profilin 2 Antibody

• D3S1319E
• PFL
• profilin 2
• Profilin II
• profilin-2

Background

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PFN2
• Entrez:
  • 5217(Human)
  • 18643(Mouse)
  • 64303(Rat)