PPAR gamma/NR1C3 Antibody (K8713)

• Reactivity: Hu
• Applications: WB, IP, ELISA, GS
• Clone: K8713
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

PPAR gamma/NR1C3 Antibody (K8713) Summary

• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPARG

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunoprecipitation
  • Direct ELISA
  • Gel Supershift Assay

Packaging, Storage & Formulations

• Storage: Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃.
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PPAR gamma/NR1C3 Antibody (K8713)

• CIMT1
• NR1C3
• NR1C3GLM1
• Nuclear receptor subfamily 1 group C member 3
• peroxisome proliferator-activated receptor gamma 1
• peroxisome proliferator-activated receptor gamma
• PPAR gamma
• PPARG
• PPARG1peroxisome proliferative activated receptor, gamma
• PPARG2PPARgamma
• PPAR-gamma

Background

Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a lipid-activated nuclear hormone receptor with roles in adipocyte differentiation, lipid and glucose metabolism, and modulation of immune and inflammatory reactions. PPAR gamma is the receptor for insulin-sensitizing thiazolidinediones, commonly used for the treatment of type 2 diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PPAR gamma/NR1C3 Antibody (PP-K8713-00)(3)

Publications using PP-K8713-00

• M Fumery, S Speca, A Langlois, AM Davila, C Dubuquoy, M Grauso, A Martin Men, M Figeac, D Metzger, C Rousseaux, JF Colombel, L Dubuquoy, P Desreumaux, B Bertin Peroxisome proliferator-activated receptor gamma (PPAR?) regulates lactase expression and activity in the gut EMBO Mol Med, 2017;0(0):. 2017 [PMID: 28947679] (Western Blot, Human)
• Al-Alem L, Southard RC, Kilgore MW, Curry TE Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARgamma independent manner. PLoS ONE, 2011;6(1):e16179. 2011 [PMID: 21283708] (Western Blot, Human)
• Huang W, Rha GB, Han MJ, Eum SY, Andras IE, Zhong Y, Hennig B, Toborek M PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells. J. Neurochem., 2008;107(2):497-509. 2008 [PMID: 18710415] (Western Blot, Human)

Bioinformatics

• Gene Symbol: PPARG