PINX1 Antibody

Western Blot: PINX1 Antibody [NBP2-19832] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PINX1 Antibody Summary

• Description: Novus Biologicals Rabbit PINX1 Antibody (NBP2-19832) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PINX1. The exact sequence is proprietary.
• Localization: Nucleus; nucleolus; Telomere
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PINX1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:500-1:3000
• Theoretical MW: 37 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (81%), Bovine (80%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for PINX1 Antibody

• FLJ20565
• hepatocellular carcinoma-related putative tumor suppressor
• Liver-related putative tumor suppressor
• LPTLPinX1
• LPTS67-11-3 protein
• MGC8850
• PIN2 interacting protein 1
• PIN2/TERF1 interacting, telomerase inhibitor 1
• PIN2/TERF1-interacting telomerase inhibitor 1
• PIN2-interacting protein 1
• Pin2-interacting protein X1
• Protein 67-11-3
• TRF1-interacting protein 1

Background

Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: PINX1
• Uniprot:
  • Q96BK5(Human)