TFIP11 Antibody

Images

 
Independent Antibodies: Western Blot: TFIP11 Antibody [NBP1-40364] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-TFIP11 ...read more
Immunohistochemistry: TFIP11 Antibody [NBP1-40364] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- TFIP11 used at a dilution of 1:200 (1ug/ml). Detection: DAB

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
Validated by:
 

Independent Antibodies

       

Order Details

TFIP11 Antibody Summary

Immunogen
The immunogen for this product maps to a region between residue 1 and 50 of human tuftelin interacting protein 11 using the numbering given in entry NP_036275.1 (GeneID 24144).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TFIP11
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TFIP11 Antibody

  • bK445C9.6
  • DKFZP434B194
  • FLJ22086
  • hNtr1
  • NTR1
  • Septin and tuftelin-interacting protein 1
  • STIP
  • STIP-1
  • TIP39Spp382
  • tuftelin interacting protein 11
  • tuftelin-interacting protein 11

Background

Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNFalpha in an ERK1/2 and Akt kinase-dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional TFIP11 Products

Array NBP1-40364

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Bioinformatics

Gene Symbol TFIP11
Entrez