PGR1 Antibody

Wild-type (WT) and PGR1 knockout (KO) HeLa cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with PGR1 antibody [N1C2] (NBP3-48527) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Prostaglandin reductase 1 antibody [N1C2] detects Prostaglandin reductase 1 protein by Western blot analysis.A. 40 ug PL45 whole cell lysate/extractB. 40 ug PANC1 whole cell lysate/extract C. 40 ug MIAPACA2 whole cell lysate/extract D. 40 ug BxPC3 whole cell lysate/extract E. 40 ug Capan2 whole cell lysate/extractProstaglandin reductase 1 antibody [N1C2] (NBP3-48527) dilution: 1:500

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PGR1 Antibody Summary

• Description: Novus Biologicals Rabbit PGR1 Antibody (NBP3-48527) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PGR1. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGR1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for PGR1 Antibody

• 15-oxoprostaglandin 13-reductase
• EC 1.3.1.-
• EC 1.3.1.48
• EC 1.3.1.74
• FLJ99229
• leukotriene B4 12-hydroxydehydrogenase
• LTB4DH
• MGC34943
• NADP-dependent leukotriene B4 12-hydroxydehydrogenase
• PGR1
• PRG-1
• prostaglandin reductase 1
• ZADH3
• zinc binding alcohol dehydrogenase domain containing 3

Background

PGR1, or Prostaglandin reductase 1, contains a 36 kDa and a 33 kDa isoform, and is involved in the conversion of leukotriene B4 to 12-oxo-leukotriene B4. Current disease research is being conducted to determine the relationship between PGR1 and alcoholism and lung cancer. The protein is linked to the synthesis of lipoxins, leukotrienes, eoxins, protaglandins, and thromboxanes, and arachidonic acid metabolism. Through these processes, PGR1 interacts with UBC, FNBP1L, HAT1, RBBP4, and HSP90AA1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTGR1