Species: Hu, Mu, Rt
Applications: WB, Flow, IHC
Host: Rabbit Monoclonal
Species: Hu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
PGR1, or Prostaglandin reductase 1, contains a 36 kDa and a 33 kDa isoform, and is involved in the conversion of leukotriene B4 to 12-oxo-leukotriene B4. Current disease research is being conducted to determine the relationship between PGR1 and alcoholism and lung cancer. The protein is linked to the synthesis of lipoxins, leukotrienes, eoxins, protaglandins, and thromboxanes, and arachidonic acid metabolism. Through these processes, PGR1 interacts with UBC, FNBP1L, HAT1, RBBP4, and HSP90AA1.
Bioinformatics
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
22949 |
Alternate Names |
- 15-oxoprostaglandin 13-reductase
- EC 1.3.1.-
- EC 1.3.1.48
- EC 1.3.1.74
- FLJ99229
- leukotriene B4 12-hydroxydehydrogenase
- LTB4DH
- MGC34943
- NADP-dependent leukotriene B4 12-hydroxydehydrogenase
- PGR1
- PRG-1
- prostaglandin reductase 1
- ZADH3
- zinc binding alcohol dehydrogenase domain containing 3
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