PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
439728
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 488
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor® 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse PGLYRP2/PGRP-L
Ser23-Asn530
Accession # Q8VCS0
Specificity
Detects mouse PGLYRP2/PGRP-L in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) PGRP-S and rmPGRP-1 beta is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
PGLYRP2
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor® 488]

  • EC 3.5.1.28
  • peptidoglycan recognition protein 2tagl-beta
  • peptidoglycan recognition protein L
  • PGLYRP2
  • PGLYRPL
  • PGLYRPLHMFT0141
  • PGRP2
  • PGRPL
  • PGRP-L
  • PGRP-LN-acetylmuramoyl-L-alanine amidase
  • PGRPLPeptidoglycan recognition protein long
  • TAGL
  • tagL-alpha
  • TAGL-like

Background

PGRP-L (peptidoglycan recognition protein‑long; also called PGRP-2 or TagL) is a 530 amino acid (aa) member of the PGRP family that is expressed in the liver. All mouse PGRPs bind peptidoglycan and Gram-positive bacteria, and may function as innate immunity pattern recognition molecules. PGRP-L is a Zn2+-dependent N‑acetylmuramoyl-L-alanine amidase that hydrolyzes cell wall glycopeptides. It contains two membrane-spanning segments, with both termini thought to be extracellular, but is also reported in serum. A truncated 450 aa isoform has been reported. Overall aa identity between mouse and human PGRP-L is 68%.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PGLYRP2
Uniprot
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