PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor™ Plus 594]

• Reactivity: Mu
• Clone: 439728
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 594

PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor™ Plus 594] Summary

• Specificity: Detects mouse PGLYRP2/PGRP-L in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) PGRP-S and rmPGRP-1 beta is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PGLYRP2/PGRP-L Antibody (439728) [Alexa Fluor™ Plus 594]

• EC 3.5.1.28
• peptidoglycan recognition protein 2tagl-beta
• peptidoglycan recognition protein L
• PGLYRP2
• PGLYRPL
• PGLYRPLHMFT0141
• PGRP2
• PGRPL
• PGRP-L
• PGRP-LN-acetylmuramoyl-L-alanine amidase
• PGRPLPeptidoglycan recognition protein long
• TAGL
• tagL-alpha
• TAGL-like

Background

PGRP-L (peptidoglycan recognition protein‑long; also called PGRP-2 or TagL) is a 530 amino acid (aa) member of the PGRP family that is expressed in the liver. All mouse PGRPs bind peptidoglycan and Gram-positive bacteria, and may function as innate immunity pattern recognition molecules. PGRP-L is a Zn²⁺-dependent N‑acetylmuramoyl-L-alanine amidase that hydrolyzes cell wall glycopeptides. It contains two membrane-spanning segments, with both termini thought to be extracellular, but is also reported in serum. A truncated 450 aa isoform has been reported. Overall aa identity between mouse and human PGRP-L is 68%.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.