PDGFR alpha Antibody (16A1) - BSA Free

Images

 
Immunocytochemistry/ Immunofluorescence: PDGFR alpha Antibody (16A1) [NBP1-44581] - Characterization of Ad vectors expressing human PDGFRalpha and EGFR. ARPE-19 epithelial, human foreskin fibroblasts (HFF), and human ...read more
Flow (Cell Surface): PDGFR alpha Antibody (16A1) [NBP1-44581] - Surface staining of CD140a in CD140a-transfected cells using anti-CD140a (16A1) purified / GAM-APC.
Flow Cytometry: PDGFR alpha Antibody (16A1) [NBP1-44581] - CD140a in CD140a-transfected 3T3 cells using anti-CD140a (16A1) APC.
Flow Cytometry: PDGFR alpha Antibody (16A1) [NBP1-44581] - CD140a in CD140a-transfected cells using anti-CD140a (16A1) PE.
Flow (Cell Surface): PDGFR alpha Antibody (16A1) [NBP1-44581] - Surface staining of CD140a in CD140a-transfected cells using anti-CD140a (16A1) FITC.
Flow (Cell Surface): PDGFR alpha Antibody (16A1) [NBP1-44581] - Surface staining of CD140a in CD140a-transfected cells using anti-CD140a (16A1) biotin / streptavidin-APC.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func, ICC/IF, CyTOF-ready
Clone
16A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

PDGFR alpha Antibody (16A1) - BSA Free Summary

Additional Information
Clone 16A1 was used by HLDA to establish CD designation.
Immunogen
CD140a-transfected NIH 3T3 cells
Specificity
The mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PDGFRA
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Cell Surface)
  • Flow Cytometry 2 ug/ml
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • In vitro assay
Application Notes
This antibody is Cytof ready. Use in In vitro reported in scientific literature (PMID: 23028311).
Theoretical MW
170 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP1-44581 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for PDGFR alpha Antibody (16A1) - BSA Free

  • alpha-type platelet-derived growth factor receptor
  • CD140 antigen-like family member A
  • CD140a antigen
  • CD140a
  • EC 2.7.10
  • EC 2.7.10.1
  • MGC74795
  • PDGF R alpha
  • PDGFR alpha
  • PDGFR2
  • PDGFRA
  • PDGFRA/BCR fusion
  • PDGF-R-alpha
  • platelet-derived growth factor receptor, alpha polypeptide
  • rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein
  • RHEPDGFRA

Background

CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PDGFR alpha Antibody (NBP1-44581)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: In vitro.


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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol PDGFRA