PDGFR alpha Research Products: Novus Biologicals

PDGFR alpha Antibodies (47)

PDGFR alpha Antibody Pair (1)

PDGFR alpha ELISA Kits (4)

PDGFR alpha Lysate (1)

PDGFR alpha Proteins (7)

Antibodies

PDGFR alpha Antibody [Unconju ...

AF1062

HAF017). Specific bands were detected for PDGF Ra at approximately 160-200 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot PDGFR alpha Antibody [Unconjugated]

Western Blot PDGFR alpha Antibody [Unconjugated]

CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody [Unconjugated]

Immunohistochemistry PDGFR alpha Antibody [Unconjugated]

CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the plasma membrane of mesenchymal cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody [Unconjugated]

221-AA) stimulates proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by Resazurin (AR002. Proliferation elicited by Recombinant Human PDGF-AA (250 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1062). The ND₅₀ is typically 0.2-1.6 µg/mL." class="big_lightbox" target="_blank"> Neutralization PDGFR alpha Antibody [Unconjugated]

Neutralization PDGFR alpha Antibody [Unconjugated]

Immunocytochemistry/ Immunofluorescence PDGFR alpha Antibody [Unconjugated]

F0108). View our protocol for Staining Membrane-associated Proteins. " class="big_lightbox" target="_blank"> Flow Cytometry PDGFR alpha Antibody [Unconjugated]

Flow Cytometry PDGFR alpha Antibody [Unconjugated]

(4 Reviews)

(360 Publications)

Species: Mu
Applications: WB, Flow, IHC, B/N
Host: Goat Polyclonal

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	AF1062U-100UG
Alexa Fluor 405	AF1062V-100UG
Alexa Fluor 488	FAB1062G
Alexa Fluor 532	AF1062X-100UG
Alexa Fluor 594	AF1062T-100UG
Alexa Fluor 647	AF1062R-100UG
Alexa Fluor 700	AF1062N-100UG
Alexa Fluor 750	AF1062S-100UG
Alexa Fluor Plus 405	AF1062AFP405-100UG
Alexa Fluor Plus 488	AF1062AFP488-100UG
Alexa Fluor Plus 555	AF1062AFP555-100UG
Alexa Fluor Plus 594	AF1062AFP594-100UG
Alexa Fluor Plus 647	AF1062AFP647-100UG
Alexa Fluor Plus 680	AF1062AFP680-100UG
Allophycocyanin	FAB1062A
Biotin	BAF1062
CoraFluor 1	AF1062CL1
DyLight 350	AF1062D
DyLight 405	AF1062E
DyLight 488	AF1062K
DyLight 550	AF1062L
DyLight 594	AF1062M
DyLight 650	AF1062W
DyLight 680	AF1062Y
DyLight 755	AF1062Z
FITC	AF1062F
HRP	AF1062H
Janelia Fluor 525	AF1062JF525
Janelia Fluor 549	AF1062I
Janelia Fluor 646	AF1062J
Janelia Fluor 669	AF1062JF669
PerCP	AF1062C
Phycoerythrin	FAB1062P
mFluor Violet 450 SE	AF1062MFV450
mFluor Violet 500 SE	AF1062MFV500
mFluor Violet 610 SE	AF1062MFV610

Formulation	Catalog #	Availability	Price
Carrier Free	FAB1062P
Carrier Free	FAB1062A
Carrier Free	FAB1062G
Carrier Free	AF1062-SP

PDGFR alpha Antibody

AF-307-NA

221-AA) stimulates proliferation in the WS-1 human fetal skin fibroblast cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human PDGF-AA (10 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human PDGF Ra Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-307-NA). The ND₅₀ is typically 1-6 µg/mL." class="big_lightbox" target="_blank"> Neutralization PDGFR alpha Antibody

CTS008) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody

Immunohistochemistry PDGFR alpha Antibody

CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody

CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to plasma membranes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody

Immunocytochemistry/ Immunofluorescence PDGFR alpha Antibody

(2 Reviews)

(62 Publications)

Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	AF-307-NAU-100UG
Alexa Fluor 405	AF-307-NAV-100UG
Alexa Fluor 488	AF-307-NAG-100UG
Alexa Fluor 532	AF-307-NAX-100UG
Alexa Fluor 594	AF-307-NAT-100UG
Alexa Fluor 647	AF-307-NAR-100UG
Alexa Fluor 700	AF-307-NAN-100UG
Alexa Fluor 750	AF-307-NAS-100UG
Alexa Fluor Plus 405	AF-307-NAAFP405
Alexa Fluor Plus 488	AF-307-NAAFP488
Alexa Fluor Plus 555	AF-307-NAAFP555
Alexa Fluor Plus 594	AF-307-NAAFP594
Alexa Fluor Plus 647	AF-307-NAAFP647
Alexa Fluor Plus 680	AF-307-NAAFP680
Allophycocyanin	AF-307-NAA
Biotin	BAF322
CoraFluor 1	AF-307-NACL1
DyLight 350	AF-307-NAD
DyLight 405	AF-307-NAE
DyLight 488	AF-307-NAK
DyLight 550	AF-307-NAL
DyLight 594	AF-307-NAM
DyLight 650	AF-307-NAW
DyLight 680	AF-307-NAY
DyLight 755	AF-307-NAZ
FITC	AF-307-NAF
HRP	AF-307-NAH
Janelia Fluor 525	AF-307-NAJF525
Janelia Fluor 549	AF-307-NAI
Janelia Fluor 646	AF-307-NAJ
Janelia Fluor 669	AF-307-NAJF669
PE	AF-307-NAP
PerCP	AF-307-NAC
mFluor Violet 450 SE	AF-307-NAMFV450
mFluor Violet 500 SE	AF-307-NAMFV500
mFluor Violet 610 SE	AF-307-NAMFV610

Formulation	Catalog #	Availability	Price
Carrier Free	AF-307-SP

PDGFR alpha Antibody (35248) ...

MAB322

6765-PR) to Recombinant Human PDGF AA (221-AA). The Neutralization Dose (ND₅₀) for this effect is typically 40.0-400 ng/mL." class="big_lightbox" target="_blank"> Neutralization PDGFR alpha Antibody (35248) [Unconjugated]

Neutralization PDGFR alpha Antibody (35248) [Unconjugated]

CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGFR alpha Antibody (35248) [Unconjugated]

Immunohistochemistry PDGFR alpha Antibody (35248) [Unconjugated]

(1 Review)

(22 Publications)

Species: Hu
Applications: WB, IHC, B/N
Host: Mouse Monoclonal

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB322U-100UG
Alexa Fluor 405	FAB322V-100UG
Alexa Fluor 488	FAB322G-100UG
Alexa Fluor 532	FAB322X-100UG
Alexa Fluor 594	FAB322T-100UG
Alexa Fluor 647	FAB322R-100UG
Alexa Fluor 700	FAB322N-100UG
Alexa Fluor 750	FAB322S-100UG
Alexa Fluor Plus 405	FAB322AFP405-100UG
Alexa Fluor Plus 488	FAB322AFP488-100UG
Alexa Fluor Plus 555	FAB322AFP555-100UG
Alexa Fluor Plus 594	FAB322AFP594-100UG
Alexa Fluor Plus 647	FAB322AFP647-100UG
Alexa Fluor Plus 680	FAB322AFP680-100UG
Allophycocyanin	FAB322A
Biotin	FAB322B
CoraFluor 1	FAB322CL1
DyLight 350	FAB322D
DyLight 405	FAB322E
DyLight 488	FAB322K
DyLight 550	FAB322L
DyLight 594	FAB322M
DyLight 650	FAB322W
DyLight 680	FAB322Y
DyLight 755	FAB322Z
FITC	FAB322F
HRP	FAB322H
Janelia Fluor 525	FAB322JF525
Janelia Fluor 549	FAB322I
Janelia Fluor 646	FAB322J
Janelia Fluor 669	FAB322JF669
PE	FAB322P
PerCP	FAB322C
mFluor Violet 450 SE	FAB322MFV450
mFluor Violet 500 SE	FAB322MFV500
mFluor Violet 610 SE	FAB322MFV610

Formulation	Catalog #	Availability	Price
Carrier Free	MAB322-SP
Carrier Free	MAB322-100
Carrier Free	MAB322-500

We have 47 PDGFR alpha Antibodies

Antibody Pairs

PDGFR alpha Antibody Pair [HR ...

NBP2-79494

Species: Hu
Applications: ELISA

Conjugate	Catalog #	Availability	Size	Price
HRP	NBP2-79494-5Plates
HRP	NBP2-79494-15Plates

We have 1 PDGFR alpha Antibody Pair

ELISA Kits

Human Phospho-PDGF R alpha Du ...

DYC2114-2

(7 Publications)

Species: Hu
Applications: ELISA

Conjugate	Catalog #	Availability	Size	Price
Biotin	DYC2114E
Biotin	DYC2114-5

Human Total PDGF R alpha DuoS ...

DYC322-2

(1 Publication)

Species: Hu
Applications: ELISA

Conjugate	Catalog #	Availability	Size	Price
Biotin	DYC322-5

Rat PDGFR alpha ELISA Kit (Co ...

NBP3-55548

Species: Rt
Applications: ELISA

We have 4 PDGFR alpha ELISA Kits

Lysates

PDGFR alpha 293T Cell Transie ...

H00005156-T01

Unknown PDGFR alpha 293T Cell Transient Overexpression Lysate

Species: Hu
Applications: WB

We have 1 PDGFR alpha Lysate

Proteins

Recombinant Human PDGF R alph ...

6765-PR

(4 Publications)

Species: Hu
Applications: Bioactivity

Formulation	Catalog #	Availability	Price
Carrier Free	6765-PR-050

Recombinant Human PDGF R alph ...

AVI10383

MAB322) is immobilized at 1 µg/mL (100 µL/well), Biotinylated Recombinant Human PDGF Ra His-tag Avi-tag (Catalog # AVI10383) binds with an ED₅₀ of 0.1-1 µg/mL." class="big_lightbox" target="_blank"> Binding Activity PDGFR alpha [Biotin]

Species: Hu
Applications: Binding Activity

Conjugate	Catalog #	Availability	Size	Price
Biotin	AVI10383-050

Formulation	Catalog #	Availability	Price
Carrier Free	AVI10383-050

Recombinant Human PDGF R alph ...

10383-PR

221-AA) is presented at 2 µg/mL (100 µL/well), Recombinant Human PDGF R alpha His-tag Protein (Catalog # 10383-PR) binds with an ED₅₀ of 2.00-16.00 µg/mL." class="big_lightbox" target="_blank"> Binding Activity PDGFR alpha [Unconjugated]

Binding Activity PDGFR alpha [Unconjugated]

Applications: Bioactivity

Formulation	Catalog #	Availability	Price
Carrier Free	10383-PR-050

We have 7 PDGFR alpha Proteins

Description

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Bioinformatics

Uniprot	AAH15186 Human ENSP00000257290 Human NM_006206 Human NP_006197 Human P16234 Human P26618 Mouse
Product By Gene ID	5156
Alternate Names	alpha-type platelet-derived growth factor receptor CD140 antigen-like family member A CD140a antigen CD140A CD140a EC 2.7.10 EC 2.7.10.1 MGC74795 PDGFR2 PDGFRA/BCR fusion PDGF-R-alpha platelet-derived growth factor receptor, alpha polypeptide rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein RHEPDGFRA

Research Areas for PDGFR alpha

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase

PDGFR alpha Products

Description

Bioinformatics

Research Areas for PDGFR alpha