PDGF R beta Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: PDGF R beta Antibody [NBP1-88134] - Staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.

Analysis in human cell line U-87 MG.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PDGF R beta Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PDGF R beta Antibody - BSA Free (NBP1-88134) is a polyclonal antibody validated for use in WB and ICC/IF. Anti-PDGF R beta Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: AQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVAL
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDGFRB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
• Control Peptide:

  PDGF R beta Protein (NBP1-88134PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PDGF R beta Antibody - BSA Free

• beta-type platelet-derived growth factor receptor
• CD140 antigen-like family member B
• CD140b antigen
• CD140b
• EC 2.7.10
• EC 2.7.10.1
• JTK12
• PDGF R beta
• PDGFR
• PDGFR1
• PDGFRB
• PDGF-R-beta
• platelet-derived growth factor receptor, beta polypeptide

Background

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PDGF R beta Antibody (NBP1-88134)(1)

Publication using NBP1-88134

• Steller EJ, Raats DA, Koster J et al. PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells. Neoplasia 2013-02-01 [PMID: 23441134] (WB, IF/IHC, Human)

Bioinformatics

• Gene Symbol: PDGFRB