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PDGF R beta Products

Antibodies
PDGF R beta Antibody [Unconju ...
PDGF R beta Antibody [Unconjugated]
AF1042
HAF019). A specific band was detected for PDGF R beta at approximately 190 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot PDGF R beta Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGF R beta Antibody [Unconjugated]
AF1042) at 1.7ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-goat IgG VisUCyte HRP Polymer Antibody (Catalog # VC004) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to developing vasculature. " class="big_lightbox" target="_blank"> In-situ Hybridization PDGF R beta Antibody [Unconjugated]
Species: Mu
Applications: WB, IHC, Dual ISH-IHC
Host: Goat Polyclonal
PDGF R beta Antibody [Unconju ...
PDGF R beta Antibody [Unconjugated]
AF385
CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry PDGF R beta Antibody [Unconjugated]
385-PR) inhibits Recombinant Human PDGF-BB (220-BB) induced proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human PDGF-BB (4 ng/mL) activity elicited by Recombinant Human PDGF R beta Fc Chimera (2 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human PDGF R beta Antigen Affinity-purified Polyclonal Antibody (Catalog # AF385). The ND50 is typically 10-40 µg/mL." class="big_lightbox" target="_blank"> Neutralization PDGF R beta Antibody [Unconjugated]
AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). View our protocol for Staining Membrane-associated Proteins. " class="big_lightbox" target="_blank"> Flow Cytometry PDGF R beta Antibody [Unconjugated]
AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). View our protocol for Staining Membrane-associated Proteins. " class="big_lightbox" target="_blank"> Flow Cytometry PDGF R beta Antibody [Unconjugated]
HAF017). A specific band was detected for PDGF R beta at approximately 190 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot PDGF R beta Antibody [Unconjugated]
Species: Hu
Applications: WB, Flow, IHC, B/N, CyTOF-ready
Host: Goat Polyclonal
PDGF R beta Antibody (PR7212) ...
PDGF R beta Antibody (PR7212) [Unc...
MAB1263
MAB002, open histogram) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). View our protocol for Staining Membrane-associated Proteins. " class="big_lightbox" target="_blank"> Flow Cytometry PDGF R beta Antibody (PR7212) [Unconjugated]
Species: Hu
Applications: WB, Flow, IP
Host: Mouse Monoclonal
Antibody Pairs
PDGF R beta Antibody Pair [HR ...
PDGF R beta Antibody Pair [HRP]
NBP2-79481
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human Phospho-PDGF R beta Duo ...
Human Phospho-PDGF R beta DuoSet I...
DYC1767-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human Total PDGF R beta DuoSe ...
Human Total PDGF R beta DuoSet IC ...
DYC385-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Human Phospho-PDGF R beta (Y7 ...
Human Phospho-PDGF R beta (Y751) D...
DYC3096-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Lysates
PDGF R beta Overexpression Ly ...
PDGF R beta Overexpression Lysate
NBL1-14239
Species: Hu
Applications: WB
Proteins
Recombinant Human PDGF R beta ...
Recombinant Human PDGF R beta Fc C...
385-PR
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse PDGF R beta ...
Recombinant Mouse PDGF R beta Fc C...
1042-PR
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human PDGF R beta ...
Recombinant Human PDGF R beta Fc C...
AVI10652
220-BB) is coated at 1 μg/mL (100 μL/well), Biotinylated Recombinant Human PDGF R beta Fc Chimera Avi-tag (Catalog # AVI10652) binds with an ED50 of 12-120 ng/mL." class="big_lightbox" target="_blank"> Binding Activity PDGF R beta [Biotin]
Species: Hu
Applications: Bioactivity
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  

Description

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Mouse
Human
Product By Gene ID 5159
Alternate Names
  • beta-type platelet-derived growth factor receptor
  • CD140 antigen-like family member B
  • CD140b antigen
  • CD140B
  • CD140b
  • EC 2.7.10
  • EC 2.7.10.1
  • JTK12
  • PDGFR
  • PDGFR1
  • PDGF-R-beta
  • platelet-derived growth factor receptor, beta polypeptide

Research Areas for PDGF R beta

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase