PBR Antibody

Images

 
Western Blot: PBR Antibody [NBP1-51934] - (1ug/ml) staining of Mouse Kidney lysate (A) and of Mouse Spleen lysate (B) (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: PBR Antibody [NBP1-51934] - Analysis of PBR in Mouse Spleen lysate (35ug protein in RIPA buffer) using NBP1-51934 at 0.2ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

PBR Antibody Summary

Immunogen
Peptide with sequence C-RDNSGRRGGSRLPE corresponding to C-Terminus according to Uniprot Mouse NP_033905.3.
Epitope
C-RDNSGRRGGSRLPE
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TSPO
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Peptide ELISA Detection limit 1:8000
Application Notes
WB: Approx. 18 kDa band observed in mouse kidney and approx. 17 kDa band doublet observed in mouse spleen lysates (calculated MW of 18.8 kDa band according to NP_033905.3).
Publications
Read Publication using NBP1-51934.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PBR Antibody

  • benzodiazepine peripheral binding site
  • BZRPDBI
  • IBP
  • MBRPBS
  • mDRC
  • Mitochondrial benzodiazepine receptor
  • PBRBPBS
  • PBRS
  • peripheral benzodiazepine receptor
  • Peripheral-type benzodiazepine receptor
  • pk18
  • PKBSbenzodiazapine receptor (peripheral)
  • PTBR
  • translocator protein (18kDa)
  • translocator protein

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PBR Antibody (NBP1-51934)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TSPO
Entrez
Uniprot