PAWR / PAR4 Antibody - BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Catalog# & Formulation Size Price

PAWR / PAR4 Antibody - BSA Free Summary

Immunogen
Synthetic peptides corresponding to the N-terminal sequence (MATGGYRTSSGLGGS) and C-terminal sequence (QENKTLLKVVGQLTR) of human PAR4.
Localization
Cytoplasm. Nucleus. Note: Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis. Nuclear localization includes nucleoplasm and PML n
Specificity
PAR4
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAWR
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500 -1:1000
Application Notes
This antibody is useful for Western blot.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
13 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
PAWR / PAR4 Overexpression Lysate

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAWR / PAR4 Antibody - BSA Free

  • Par-4
  • PAR4prostate apoptosis response protein 4
  • PRKC apoptosis WT1 regulator protein
  • PRKC, apoptosis, WT1, regulator
  • Prostate apoptosis response 4 protein
  • prostate apoptosis response protein PAR-4
  • transcriptional repressor PAR4
  • WT1-interacting protein

Background

The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. Par-4 (for prostate apoptosis response) is a WT1-interacting protein that also functions as a transcriptional repressor. Par-4 contains a putative leucine zipper domain and is specifically upregulated during apoptosis of prostate cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PAWR
Entrez
Uniprot