This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PADI2 Antibody (4D4)
peptidlyarginine deiminase type II
peptidyl arginine deiminase, type II
Peptidylarginine Deiminase II
protein arginine deiminase
Protein-arginine deiminase type II
protein-arginine deiminase type-2
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.