PADI2 Products

Antibodies
PADI2 Antibody
PADI2 Antibody
AF7257
Species: Hu
Applications: IHC
Host: Sheep Polyclonal
PADI2 Antibody (4D4)
PADI2 Antibody (4D4)
H00011240-M01
Species: Hu, Mu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
PADI2 Antibody
PADI2 Antibody
NBP1-54958
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
PADI2 Overexpression Lysate ( ...
PADI2 Overexpression Lysate (Native)
NBP2-10366
Applications: WB
Proteins
PADI2 Partial Recombinant Pro ...
PADI2 Partial Recombinant Protein
H00011240-Q01
Species: Hu
Applications: WB, ELISA, PA
PADI2 Recombinant Protein Ant ...
PADI2 Recombinant Protein Antigen
NBP2-37918PEP
Species: Hu
Applications: AC
RNAi
PADI2 RNAi
PADI2 RNAi
H00011240-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PADI2 / PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Each family member has a distinct substrate specificity and tissue expression pattern. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative disorders, including Alzheimers disease and multiple sclerosis, and it has also been implicated in the pathogenesis of glaucoma.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 11240
Alternate Names
  • protein-arginine deiminase type-2
  • PAD-H19
  • protein arginine deiminase
  • Protein-arginine deiminase type II
  • peptidlyarginine deiminase type II
  • Peptidylarginine deiminase II
  • KIAA0994PDI2PAD2
  • EC 3.5.3.15
  • peptidyl arginine deiminase, type II

PTMs for PADI2

Learn more about PTMs related to PADI2.

Citrullination
Cleavage

Bioinformatics Tool for PADI2

Discover related pathways, diseases and genes to PADI2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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