PACS2 Antibody - BSA Free

Western Blot: PACS2 Antibody [NBP2-81975] - Analysis of PACS2 in mouse brain tissue lysate with PACS2 antibody at 1 ug/ml.

Immunocytochemistry/ Immunofluorescence: PACS2 Antibody - BSA Free [NBP2-81975] - Immunofluorescence of PACS2 in mouse brain tissue with PACS2 antibody at 20 u/ml.Red: PACS2 Antibody Blue: DAPI staining

Immunohistochemistry: PACS2 Antibody - BSA Free [NBP2-81975] - Immunohistochemistry of PACS2 in mouse brain tissue with PACS2 antibody at 5 u/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

PACS2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PACS2 Antibody - BSA Free (NBP2-81975) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. The immunogen is located within amino acids 330 - 380 of PACS2. Amino Acid Squence: ARSHKEPPSPADVPEKT
• Specificity: PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist; this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PACS2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin
  • Western Blot 1-2 ug/ml
• Theoretical MW: 95 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for PACS2 Antibody - BSA Free

• FLJ25488
• KIAA0602phosphofurin acidic cluster sorting protein 1-like
• PACS1L
• PACS1-like protein
• PACS-2
• phosphofurin acidic cluster sorting protein 2

Background

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PACS2