PACS2 Products

Antibodies
Proteins
Recombinant Human PACS2 GST ( ...
Recombinant Human PACS2 GST (N-Ter...
H00023241-P01
Species: Hu
Applications: WB, ELISA, MA, AP
PACS2 Recombinant Protein Ant ...
PACS2 Recombinant Protein Antigen
NBP1-81496PEP
Species: Hu
Applications: AC
PACS2 Recombinant Protein Ant ...
PACS2 Recombinant Protein Antigen
NBP2-58824PEP
Species: Hu
Applications: AC

Description

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments

Bioinformatics

Uniprot Human
Human
Product By Gene ID 23241
Alternate Names
  • FLJ25488
  • KIAA0602phosphofurin acidic cluster sorting protein 1-like
  • PACS1L
  • PACS1-like protein
  • PACS-2
  • phosphofurin acidic cluster sorting protein 2