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HEK293T cells were seeded and fixed with 4% PFA. The primary antibody for IF was used at a dilution ratio of 1:50. Image from a verified customer review.
PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. The immunogen is located within amino acids 330 - 380 of PACS2.
Specificity
PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist; this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PACS2
Purity
Peptide affinity purified
Innovator's Reward
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Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for PACS2 Antibody [Alexa Fluor® 488]
FLJ25488
KIAA0602phosphofurin acidic cluster sorting protein 1-like
PACS1L
PACS1-like protein
PACS-2
phosphofurin acidic cluster sorting protein 2
Background
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Mouse was perfused with PFA, and brain sections were prepared using a cryosectioning method. The primary antibody for IF was used at a dilution ratio of 1:50.
HEK293T cells were seeded and fixed with 4% PFA. The primary antibody for IF was used at a dilution ratio of 1:50.
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