OSCAR Antibody (RM0300-11E34) - Azide and BSA Free

• Reactivity: Mu
• Applications: WB
• Clone: RM0300-11E34
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

OSCAR Antibody (RM0300-11E34) - Azide and BSA Free Summary

• Immunogen: Mouse recombinant OSCAR (extracellular domain)
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: OSCAR
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A or G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for OSCAR Antibody (RM0300-11E34) - Azide and BSA Free

• hOSCAR
• MGC33613
• OSCAR
• osteoclast associated receptor OSCAR-S1
• osteoclast associated receptor OSCAR-S2
• osteoclast associated, immunoglobulin-like receptor
• osteoclast-associated immunoglobulin-like receptor
• Osteoclast-associated receptor
• PIGR3
• PIgR-3
• Poly-Ig receptor 3
• Polymeric immunoglobulin receptor 3

Background

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OSCAR Antibody (NBP2-11836)(1)

Publication using NBP2-11836

• Negishi-Koga T, Gober HJ, Sumiya E et al. Immune complexes regulate bone metabolism through FcR-gamma signalling Nat Commun 2015-03-31 [PMID: 25824719] (WB, Mouse)

Bioinformatics

• Gene Symbol: OSCAR
• Uniprot:
  • Q8VBT3()