Olig2 Products

Description

Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. OIlig2 is expressed in the ventral spinal cord as early as 9.5 dpc and is scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. (Arnett et al., 2004) From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).

Bioinformatics

Uniprot	AAH36245.1 Human NP_005797 Human Q13516 Human Q9EQW6 Mouse
Product By Gene ID	10215
Alternate Names	bHLHb1 BHLHB1 BHLHE19 Class B basic helix-loop-helix protein 1 Class E basic helix-loop-helix protein 19 human protein kinase C-binding protein RACK17 OLIGO2 Oligo2 oligodendrocyte lineage transcription factor 2 oligodendrocyte transcription factor 2 oligodendrocyte-specific bHLH transcription factor 2 protein kinase C binding protein 2 Protein kinase C-binding protein 2 Protein kinase C-binding protein RACK17 RACK17helix-loop-helix protein, class B, 1

Research Areas for Olig2

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Chromatin Research
Glia Markers
Neuronal Stem Cell Markers
Neuroscience
Oligodendrocyte Cell Markers
Stem Cell Markers
Transcription Factors and Regulators