Olig2 Antibody Pair

Product Discontinued

Olig2 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: mouse monoclonal anti-OLIG2 (300 ug)
• Antibody pair for WB: rabbit polyclonal anti-OLIG2 (50 ul)
• Clonality: Polyclonal
• Gene: OLIG2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Olig2 Antibody Pair

• BHLHB1
• BHLHE19
• Class B basic helix-loop-helix protein 1
• Class E basic helix-loop-helix protein 19
• human protein kinase C-binding protein RACK17
• Olig2
• OLIGO2
• oligodendrocyte lineage transcription factor 2
• oligodendrocyte transcription factor 2
• oligodendrocyte-specific bHLH transcription factor 2
• PRKCBP2
• protein kinase C binding protein 2
• Protein kinase C-binding protein 2
• Protein kinase C-binding protein RACK17
• RACK17
• RACK17helix-loop-helix protein, class B, 1

Background

Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. OIlig2 is expressed in the ventral spinal cord as early as 9.5 dpc and is scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. (Arnett et al., 2004) From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: OLIG2