NR4A3/NOR1 Antibody

Images

 
Immunohistochemistry-Paraffin: NR4A3/NOR1 Antibody [NLS2341] - Analysis of anti-Nor-1 / NR4A3 antibody with human skin, melanoma.
Immunohistochemistry-Paraffin: NR4A3/NOR1 Antibody [NLS2341] - Analysis of anti-Nor-1 / NR4A3 antibody with human brain, neurons and glia.

Product Details

Summary
Reactivity Hu, Bt, Ca, Mk, Mu, Rt, Po, Bv, Ha, Pm, RbSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

NR4A3/NOR1 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from near C-terminus of human NR4A3.
Specificity
Human NR4A3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (90%), Rat (95%), Porcine (95%), Rabbit (95%), Primate (95%), Hamster (95%), Bovine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NR4A3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500
Positive Control
NR4A3/NOR1 Lysate (NBL1-13781)
Publications
Read Publications using
NLS2341 in the following applications:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Elephant (100%), Panda (100%), Marmoset (95%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NR4A3/NOR1 Antibody

  • CHN
  • CSMF
  • MINOR
  • NOR1
  • TEC

Background

NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant. NOR-1 expression has been documented in human brain, heart, placenta, kidney, skeletal muscle, fetal brain and fetal lung. ESTs have been isolated from human tissue libraries, including cancerous head/neck and skin, and normal prostate, skin, liver, testis, skeletal muscle, blood and B-cell/lung/testis. Caution: The symbol NOR-1 is also used to describe a nitric oxide-donor reagent. Tec is also the name of a kinase on chromosome 4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NR4A3/NOR1 Antibody (NLS2341)(2)

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Product General Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NR4A3
Entrez
Uniprot