NKIRAS2 Antibody

Images

 
Western Blot: NKIRAS2 Antibody [NBP2-19545] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE gel, diluted at 1:500.
Immunohistochemistry-Paraffin: NKIRAS2 Antibody [NBP2-19545] - Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ch, Pm, RMSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

NKIRAS2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human NKIRAS2. The exact sequence is proprietary.
Localization
Cytoplasm
Predicted Species
Mouse (98%), Rat (98%), Chicken (92%), Primate (99%), Rhesus Macaque (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NKIRAS2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (99%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for NKIRAS2 Antibody

  • DKFZP434N1526
  • I-kappa-B-interacting Ras-like protein 2
  • Kappa B-Ras protein 2
  • kappaB-Ras2
  • KBRAS2DKFZp434N1526
  • MGC74742
  • NF-kappa-B inhibitor-interacting Ras-like protein 2
  • NFKB inhibitor interacting Ras-like 2
  • NFKB inhibitor interacting Ras-like protein 2

Background

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NKIRAS2
Uniprot