NKIRAS2 Products

Description

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB

Bioinformatics

Uniprot	AAH07450 Human NM_017595 Human NP_001001349 Human NP_001138399 Human NP_060065 Human Q9NYR9 Human
Product By Gene ID	28511
Alternate Names	DKFZP434N1526 I-kappa-B-interacting Ras-like protein 2 Kappa B-Ras protein 2 KappaB-Ras2 kappaB-Ras2 KBRAS2DKFZp434N1526 MGC74742 NF-kappa-B inhibitor-interacting Ras-like protein 2 NFKB inhibitor interacting Ras-like 2 NFKB inhibitor interacting Ras-like protein 2

Research Areas for NKIRAS2

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Signal Transduction