Myeloperoxidase/MPO Antibody (392105) [Unconjugated]


Western blot shows lysates of HL‑60 human acute promyelocytic leukemia cell line and human neutrophil. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Myeloperoxidase/MPO Monoclonal Antibody (Catalog # more
Myeloperoxidase/MPO was detected in immersion fixed MOLT-4 human acute lymphoblastic leukemia cell line using 8 µg/mL Mouse Anti-Human Myeloperoxidase/MPO Monoclonal Antibody (Catalog # MAB3174) for 3 hours at room more
Myeloperoxidase/MPO was detected in immersion fixed HL‑60 human acute promyelocytic leukemia cell line using Mouse Anti-Human Myeloperoxidase/MPO Mono­clonal Antibody (Catalog # MAB3174) at 10 µg/mL for 3 hours more
Myeloperoxidase/MPO was detected in immersion fixed paraffin-embedded sections of human spleen using 15 µg/mL Mouse Anti-Human Myeloperoxidase/MPO Monoclonal Antibody (Catalog # MAB3174) overnight at 4 °C. Before more
Myeloperoxidase/MPO was detected in immersion fixed paraffin-embedded sections of mouse spleen using Mouse Anti-Human Myeloperoxidase/MPO Monoclonal Antibody (Catalog # MAB3174) at 10 µg/mL for 1 hour at room more

Product Details

Reactivity HuSpecies Glossary
Applications WB, IHC, ICC/IF

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Myeloperoxidase/MPO Antibody (392105) [Unconjugated] Summary

E. coli-derived recombinant human Myeloperoxidase/MPO
Accession # P05164
Detects human Myeloperoxidase/MPO in Western blots. No cross-reactivity with recombinant human Eosinophil Peroxidase is observed.
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry 8-25 ug/mL
  • Immunohistochemistry 8-25 ug/mL
  • Western Blot 1 ug/mL
Read Publications using
MAB3174 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Myeloperoxidase/MPO Antibody (392105) [Unconjugated]

  • EC 1.11.1
  • EC
  • MPO
  • Myeloperoxidase


Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily. MPO is synthesized as a preproprotein that undergoes proteolytic processing to generate a disulfide-linked heterodimer of the N-terminal beta -subunit (12 kDa) and C-terminal alpha subunit (60 kDa). Active MPO is a tetramer of two beta -subunits and two alpha -subunits that are also disulfide-linked through the two alpha -subunits. MPO is stored in granules and is an abundant protein in neutrophils and monocytes. MPO is released upon activation to catalyze the formation of powerful oxidants such as hypochlorous acid, which kills microbes. Unprocessed pro-MPO can also be released. Human and mouse MPO share 87% amino acid sequence identity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Myeloperoxidase/MPO Antibody (MAB3174)(9)

We have publications tested in 3 confirmed species: Human, Mouse, Gerbil.

We have publications tested in 4 applications: ELISA Capture, IHC, IHC-P, Western Blot.

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ELISA Capture
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Showing Publications 1 - 9 of 9.
Publications using MAB3174 Applications Species
F Peng, J Xie, H Liu, Y Zheng, X Qian, R Zhou, H Zhong, Y Zhang, M Li Shifting focus from bacteria to host neutrophil extracellular traps of biodegradable pure Zn to combat implant centered infection Bioactive materials, 2023;21(0):436-449. 2023 [PMID: 36185738] (ELISA Capture, Mouse) ELISA Capture Mouse
JS O'Connell, B Li, A Zito, A Ahmed, M Cadete, N Ganji, E Lau, M Alganabi, N Farhat, C Lee, S Eaton, R Mitchell, S Ray, P De Coppi, K Patel, A Pierro Treatment of necrotizing enterocolitis by conditioned medium derived from human amniotic fluid stem cells PLoS ONE, 2021;16(12):e0260522. 2021 [PMID: 34855833] (IHC, Human) IHC Human
V Puhl, H Bonnekoh, J Scheffel, T Hawro, K Weller, P von den Dr, HJ Röwert-Hub, J Cardoso, M Gonçalo, M Maurer, K Krause A novel histopathological scoring system to distinguish urticarial vasculitis from chronic spontaneous urticaria Clinical and translational allergy, 2021;11(2):e12031. 2021 [PMID: 33949135] (IHC, Human) IHC Human
C Jaworek, Y Verel-Yilm, S Driesch, S Ostgathe, L Cook, S Wagner, DK Bartsch, EP Slater, JW Bartsch Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma Journal of personalized medicine, 2021;11(2):. 2021 [PMID: 33578644] (IHC, Human) IHC Human
C Widmann, C Gandin, A Petit-Pait, M Lazdunski, C Heurteaux The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia Sci Rep, 2018;8(1):18062. 2018 [PMID: 30584250] (IHC, Mouse) IHC Mouse
X Zhang, L Wei, J Wang, Z Qin, J Wang, Y Lu, X Zheng, Q Peng, Q Ye, F Ai, P Liu, S Wang, G Li, S Shen, J Ma Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice Front Immunol, 2017;8(0):1774. 2017 [PMID: 29326691] (IHC-P, Mouse) IHC-P Mouse
H Hosoda, K Nakamura, Z Hu, H Tamura, J Reich, K Kuwahara-A, T Iba, Y Tabe, I Nagaoaka Antimicrobial cathelicidin peptide LL?37 induces NET formation and suppresses the inflammatory response in a mouse septic model Mol Med Rep, 2017;0(0):. 2017 [PMID: 28849130] (Human) Human
Sahraoui A, Dewachter C, de Medina G, Naeije R, Aouichat Bouguerra S, Dewachter L Myocardial Structural and Biological Anomalies Induced by High Fat Diet in Psammomys obesus Gerbils. PLoS ONE, 2016;11(2):e0148117. 2016 [PMID: 26840416] (IHC-P, Gerbil) IHC-P Gerbil
Ero-Tolliver I, Hudson B, Bhave G The Ancient Immunoglobulin Domains of Peroxidasin Are Required to Form Sulfilimine Cross-links in Collagen IV. J Biol Chem, 2015;290(35):21741-8. 2015 [PMID: 26178375] (Western Blot, Human) Western Blot Human

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Gene Symbol MPO