Myeloperoxidase/MPO Products

Antibodies
Myeloperoxidase/MPO Antibody ...
Myeloperoxidase/MPO Antibody [Unco...
AF3667
Species: Hu, Mu
Applications: WB, Simple Western, IHC, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Myeloperoxidase/MPO Antibody ...
Myeloperoxidase/MPO Antibody (392105)
MAB3174
Species: Hu, Mu
Applications: WB, IHC, ICC
Host: Mouse Monoclonal
Myeloperoxidase/MPO Antibody
Myeloperoxidase/MPO Antibody
NBP1-42591
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ELISA Kits
Myeloperoxidase/MPO ELISA Kit ...
Myeloperoxidase/MPO ELISA Kit [HRP]
KA0537
Species: Hu
Myeloperoxidase/MPO ELISA Kit ...
Myeloperoxidase/MPO ELISA Kit [HRP]
KA2179
Species: Mu
Kits
Myeloperoxidase/MPO Assay Kit ...
Myeloperoxidase/MPO Assay Kit
KA1338
Applications: Func
Myeloperoxidase/MPO Assay/Inh ...
Myeloperoxidase/MPO Assay/Inhibito...
KA1337
Applications: Func
Myeloperoxidase/MPO Assay Kit ...
Myeloperoxidase/MPO Assay Kit
KA1336
Applications: Func
Lysates
Myeloperoxidase/MPO Overexpre ...
Myeloperoxidase/MPO Overexpression...
NBL1-13201
Applications: WB
Proteins
Myeloperoxidase/MPO Recombina ...
Myeloperoxidase/MPO Recombinant Pr...
NBP1-87556PEP
Species: Hu
Applications: AC
Myeloperoxidase/MPO Partial R ...
Myeloperoxidase/MPO Partial Recomb...
H00004353-Q01
Species: Hu
Applications: WB, ELISA, PA
Myeloperoxidase/MPO Recombina ...
Myeloperoxidase/MPO Recombinant Pr...
NBP2-38922PEP
Species: Hu
Applications: AC
RNAi
Myeloperoxidase/MPO RNAi
Myeloperoxidase/MPO RNAi
H00004353-R01
Species: Hu

Description

FUNCTION: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. MPO is an important marker for myeloid cells, from the promyelocyte stage and to the mature forms. CATALYTIC ACTIVITY: Donor + H2O2 = oxidized donor + 2 H2O. CATALYTIC ACTIVITY: Cl- + H2O2 = HOCl + 2 H2O. COFACTOR: Binds 1 calcium ion per heterodimer. COFACTOR: Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer. SUBUNIT: Tetramer of two light chains and two heavy chains. SUBCELLULAR LOCATION: Lysosome. ALTERNATIVE PRODUCTS: 3 named isoforms produced by alternative splicing. DISEASE: Defects in MPO are the cause of myeloperoxidase deficiency (MPD). MPD is an autosomal recessive defect that results in disseminated candidiasis. SIMILARITY: Belongs to the peroxidase family. XPO subfamily.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4353
Alternate Names
  • EC 1.11.1
  • EC 1.11.1.7
  • myeloperoxidase

Research Areas for Myeloperoxidase/MPO

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Immunology
Innate Immunity
Lipid and Metabolism

Bioinformatics Tool for Myeloperoxidase/MPO

Discover related pathways, diseases and genes to Myeloperoxidase/MPO. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.