Myeloperoxidase/MPO Products

Antibodies
Myeloperoxidase/MPO Antibody ...
Myeloperoxidase/MPO Antibody [Unco...
AF3667
Species: Hu, Mu
Applications: WB, Simple Western, IHC, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
Myeloperoxidase/MPO Antibody ...
Myeloperoxidase/MPO Antibody (8F4)
NBP1-51148
Species: Mu, Rt
Applications: Flow, IA, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Myeloperoxidase/MPO Antibody ...
Myeloperoxidase/MPO Antibody (3921...
MAB3174
Species: Hu
Applications: WB, IHC, ICC/IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Mouse Myeloperoxidase DuoSet ...
Mouse Myeloperoxidase DuoSet ELISA...
DY3667
Species: Mu
Applications: ELISA
Human Myeloperoxidase DuoSet ...
Human Myeloperoxidase DuoSet ELISA...
DY3174
Species: Hu
Applications: ELISA
Human Myeloperoxidase/MPO ELI ...
Human Myeloperoxidase/MPO ELISA Ki...
NBP2-60581
Species: Hu
Applications: ELISA
Kits
Myeloperoxidase/MPO Assay Kit ...
Myeloperoxidase/MPO Assay Kit (Flu...
KA1336
Applications: Func
Myeloperoxidase/MPO Inhibitor ...
Myeloperoxidase/MPO Inhibitor Scre...
KA1337
Applications: Func
Lysates
Myeloperoxidase/MPO Overexpre ...
Myeloperoxidase/MPO Overexpression...
NBL1-13201
Species: Hu
Applications: WB
Proteins
Recombinant Human Myeloperoxi ...
Recombinant Human Myeloperoxidase ...
3174-MP
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Mouse Myeloperoxi ...
Recombinant Mouse Myeloperoxidase ...
3667-MP
Species: Mu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Myeloperoxidase/MPO Recombina ...
Myeloperoxidase/MPO Recombinant Pr...
NBP1-87556PEP
Species: Hu
Applications: AC

Description

FUNCTION: Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. MPO is an important marker for myeloid cells, from the promyelocyte stage and to the mature forms. CATALYTIC ACTIVITY: Donor + H2O2 = oxidized donor + 2 H2O. CATALYTIC ACTIVITY: Cl- + H2O2 = HOCl + 2 H2O. COFACTOR: Binds 1 calcium ion per heterodimer. COFACTOR: Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer. SUBUNIT: Tetramer of two light chains and two heavy chains. SUBCELLULAR LOCATION: Lysosome. ALTERNATIVE PRODUCTS: 3 named isoforms produced by alternative splicing. DISEASE: Defects in MPO are the cause of myeloperoxidase deficiency (MPD). MPD is an autosomal recessive defect that results in disseminated candidiasis. SIMILARITY: Belongs to the peroxidase family. XPO subfamily.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4353
Alternate Names
  • EC 1.11.1
  • EC 1.11.1.7
  • myeloperoxidase

Research Areas for Myeloperoxidase/MPO

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Immunology
Innate Immunity
Lipid and Metabolism

Bioinformatics Tool for Myeloperoxidase/MPO

Discover related pathways, diseases and genes to Myeloperoxidase/MPO. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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