MRP1 Antibody (IU2H10) [FITC]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ELISA, Flow, ICC/IF
Clone
IU2H10
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

MRP1 Antibody (IU2H10) [FITC] Summary

Immunogen
Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].
Epitope
Amino acids 8-17 of human MRP1.
Localization
Membrane
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ABCC1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
Application Notes
This MRP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot. In Western blot a band was observed at ~170-190 kDa in transfected samples. There may be a lower MW band that is a degredation product. Flow Cytometry, Immunoprecipitation and ELISA were reported in scientific literature.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MRP1 Antibody (IU2H10) [FITC]

  • ABC29
  • ABCC
  • ABCC1
  • ATP-binding cassette sub-family C member 1
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • EC 3.6.3
  • EC 3.6.3.44
  • GS-X
  • Leukotriene C(4) transporter
  • LTC4 transporter
  • MRP1
  • MRP1DKFZp781G125
  • MRPDKFZp686N04233
  • multidrug resistance associated protein 1
  • multidrug resistance protein
  • multidrug resistance-associated protein 1
  • multiple drug resistance protein 1
  • multiple drug resistance-associated protein

Background

The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MRP1 Antibody (NB400-156F) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for MRP1 Antibody (NB400-156F) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB400-156B
DyLight 405 Labeled NB400-156V
DyLight 488 Labeled NB400-156G
DyLight 550 Labeled NB400-156R
DyLight 650 Labeled NB400-156C
HRP Labeled NB400-156H

Additional MRP1 Products

MRP1 NB400-156F

Bioinformatics Tool for MRP1 Antibody (NB400-156F)

Discover related pathways, diseases and genes to MRP1 Antibody (NB400-156F). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for MRP1 Antibody (NB400-156F)

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Pathways for MRP1 Antibody (NB400-156F)

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PTMs for MRP1 Antibody (NB400-156F)

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Research Areas for MRP1 Antibody (NB400-156F)

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Blogs on MRP1.

ABC Membrane transporters and the role of MRP1 in drug resistance
ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes.  Multidrug resistance-associated protein 1 (MRP1) is a member o...  Read full blog post.

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Bioinformatics

Gene Symbol ABCC1
Entrez