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Mouse ICAM-1/CD54 Quantikine ELISA Kit

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse ICAM-1/CD54 Quantikine ELISA Kit Summary

Background
The Quantikine Mouse sICAM-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse sICAM-1 levels in cell culture supernates, tissue homogenates, serum, and plasma. It contains NS0-expressed, recombinant mouse sICAM-1 and antibodies raised against the recombinant protein. Results obtained for naturally occurring mouse sICAM-1 showed linear curves that were parallel to the sta...ndard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural mouse sICAM-1.
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Specificity
Natural and recombinant mouse sICAM-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Icam1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MIC100.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse ICAM-1/CD54 Quantikine ELISA Kit

  • BB2
  • CD54 antigen
  • CD54
  • cell surface glycoprotein P3.58
  • human rhinovirus receptor
  • ICAM1
  • ICAM-1
  • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
  • intercellular adhesion molecule 1
  • Major group rhinovirus receptor
  • P3.58

Background

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for ICAM-1/CD54 (MIC100)(30)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
(30)
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Showing Publications 1 - 10 of 30. Show All 30 Publications.
Publications using MIC100 Applications Species
K Zhong, Y Huang, PLM Zilundu, Y Wang, Y Zhou, G Yu, R Fu, SK Chung, Y Tang, X Cheng, L Zhou Motor neuron survival is associated with reduced neuroinflammation and increased autophagy after brachial plexus avulsion injury in aldose reductase-deficient mice Journal of Neuroinflammation, 2022-11-09;19(1):271. 2022-11-09 [PMID: 36352421] (Mouse) Mouse
P Nallasamy, ZY Kang, X Sun, PV Anandh Bab, D Liu, Z Jia Natural Compound Resveratrol Attenuates TNF-Alpha-Induced Vascular Dysfunction in Mice and Human Endothelial Cells: The Involvement of the NF-kappaB Signaling Pathway International Journal of Molecular Sciences, 2021-11-19;22(22):. 2021-11-19 [PMID: 34830366] (Mouse) Mouse
F Cheng, H Chang, F Yan, A Yang, J Liu, Y Liu Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells Drug Design, Development and Therapy, 2020-12-18;14(0):5589-5598. 2020-12-18 [PMID: 33376303] (Mouse) Mouse
K Chiu, ST Bashir, RA Nowak, W Mei, JA Flaws Subacute exposure to di-isononyl phthalate alters the morphology, endocrine function, and immune system in the colon of adult female mice Sci Rep, 2020-11-02;10(1):18788. 2020-11-02 [PMID: 33139756] (Mouse) Mouse
CW Liu, TL Lee, YC Chen, CJ Liang, SH Wang, JH Lue, JS Tsai, SW Lee, SH Chen, YF Yang, TY Chuang, YL Chen PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-?B-dependent pathway Part Fibre Toxicol, 2018-01-12;15(1):4. 2018-01-12 [PMID: 29329563] (Mouse) Mouse
HS Cheng, R Besla, A Li, Z Chen, EA Shikatani, M Nazari-Jah, A Hammoutène, MA Nguyen, M Geoffrion, L Cai, N Khyzha, T Li, SA MacParland, M Husain, MI Cybulsky, CM Boulanger, RE Temel, A Schober, KJ Rayner, C Robbins, JE Fish Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a Circ. Res., 2017-06-21;0(0):. 2017-06-21 [PMID: 28637783] (Mouse) Mouse
S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa J Neuroinflammation, 2017-02-20;14(1):39. 2017-02-20 [PMID: 28219400] (Mouse) Mouse
Fabiola González-H Simvastatin attenuates endothelial activation through 15-epi-lipoxin A4 production in murine chronic Chagas cardiomyopathy Antimicrob. Agents Chemother, 2017-02-23;0(0):. 2017-02-23 [PMID: 27993857] (Mouse) Mouse
Lagrange J, Li Z, Fassot C, Bourhim M, Louis H, Nguyen Dinh Cat A, Parlakian A, Wahl D, Lacolley P, Jaisser F, Regnault V Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice. FASEB J, 2014-01-22;28(5):2062-72. 2014-01-22 [PMID: 24451386] (Mouse) Mouse
Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma. Biomark Insights, 2012-07-10;7(0):87-104. 2012-07-10 [PMID: 22837640] (Mouse) Mouse
Show All 30 Publications.

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Bioinformatics

Gene Symbol Icam1