MOG Antibody (CL2858) - Azide and BSA Free

Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human Cerebral Cortex tissue

Staining of human cerebellum shows strong positivity in myelinated neural fibers.

Staining of human cerebral cortex shows strong positivity in myelinated neural fibers.

Staining of rat brain shows strong positivity in myelinated neural fibers in the cerebral cortex.

Staining of mouse brain shows strong positivity in myelinated neural fibers in the cerebellum.

Staining of rat cerebral cortex shows strong immunoreactivity in myelinated neural fibers.

Staining of mouse basal forebrain shows strong positivity in myelinated neural fibers in the caudate putamen.

Staining of human tonsil shows no positivity in lymphoid cells as expected.

Staining of rat brain shows strong positivity in myelinated neural fibers in the cerebellum.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: CL2858
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

MOG Antibody (CL2858) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse MOG Antibody (CL2858) - Azide and BSA Free (NBP2-46634) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was generated using a recombinant protein sequence of Q16653, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MOG
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS with Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Alternate Names for MOG Antibody (CL2858) - Azide and BSA Free

• MGC26137
• MOG Ig-AluB
• MOG
• MOGIG2
• myelin oligodendrocyte glycoprotein
• myelin-oligodendrocyte glycoprotein

Background

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MOG