MMP-3 Antibody Summary
A synthetic peptide made to an C-terminal portion of the human MMP3 protein (between residues 400-477) [UniProt P08254]
Mesenchymal Cells Marker
Immunogen affinity purified
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Immunogen affinity purified
- Western Blot 1:500- 1:1000
- Immunohistochemistry 1:50-1:200
- Immunohistochemistry-Paraffin 1:50-1:100
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Alternate Names for MMP-3 Antibody
- EC 3.4.24
- EC 220.127.116.11
- matrix metallopeptidase 3 (stromelysin 1, progelatinase)
- matrix metalloproteinase 3 (stromelysin 1, progelatinase)
- Matrix metalloproteinase-3
- Stromelysin 1
Matrix metalloproteinase 3 (MMP3), also known as Stromelysin-1, SL-1, and STMY1, is a member of the matrix metalloproteinase (MMP) family. Members of the MMP family are involved in the breakdown of the extracellular matrix in response to normal physiological and disease processes; these processes include embryonic development, reproduction, tissue remodeling, arthritis and metastasis. The majority of MMP proteins are secreted into the extracellular matrix as inactive proproteins; they are activated when cleaved by an extracellular proteinase. The MMP3 gene contains four hemopexin-like domains, and is part of a cluster of MMP genes that localize to chromosome 11q22.3. This gene encodes the MMP3 enzyme that degrades fibronectin, laminin, gelatins (type I, III, IV and V), collagens (type III, IV, X, and IX), and cartilage proteoglycans. Additionally, the MMP3 enzyme activates procollagenase. Areas of interest for MMP3 include wound repair, progression of atherosclerosis, and tumor initiation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Applications: WB, IHC
Applications: WB, Simple Western, ICC
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Other Available Formats
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