Human Pro-MMP-10 Quantikine ELISA Kit Summary
Background |
The Quantikine Human Pro-MMP-10 Immunoassay is a 4.5 hour solid phase immunoassay designed to measure pro-MMP-10 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human pro-MMP-10 and antibodies raised against the recombinant protein. This kit will not detect human active MMP-10 existing in either free or TIMP-bound form. Natural human pro-MMP-10 showed dos...e-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards, indicating that this kit can be used to determine relative levels of natural human pro-MMP-10. |
Specificity |
Natural and recombinant human pro-MMP-10 |
Source |
N/A |
Assay Type |
Solid Phase Sandwich ELISA |
Inter-Assay |
|
Intra-Assay |
|
Spike Recovery |
|
Sample Volume |
|
Gene |
MMP10 |
Applications/Dilutions
Dilutions |
|
Application Notes |
No significant interference observed with available related molecules. |
Publications |
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Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 degreesC. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Pro-MMP-10 Quantikine ELISA Kit
Background
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for MMP-10 (DM1000). (Showing 1 - 1 of 1 FAQs).
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wondering what the difference is between your quantikine and duo set elisas?
- Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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