Human Total MMP-7 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human Total MMP-7 Quantikine ELISA Kit Summary

Background
The Quantikine Human MMP-7 Immunoassay is a 4.5 hour solid phase ELISA designed to measure MMP-7 in cell culture supernates, serum, plasma, saliva, and urine. It contains NS0-expressed recombinant human MMP-7 and antibodies raised against the recombinant factor. The Quantikine kit detected both pro- and active forms of recombinant human MMP-7. Natural human MMP-7 showed dose-response curves ...that were parallel to the standard curves obtained using the kit standards, indicating that this kit can be used to determine relative levels of natural human MMP-7.
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Specificity
Natural and recombinant human MMP-7
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
MMP7

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DMP700.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total MMP-7 Quantikine ELISA Kit

  • EC 3.4.24
  • EC 3.4.24.23
  • Matrilysin
  • matrin
  • matrix metallopeptidase 7 (matrilysin, uterine)
  • matrix metalloproteinase 7 (matrilysin, uterine)
  • Matrix metalloproteinase-7
  • MMP7
  • MMP-7
  • MPSL1
  • Pump-1 protease
  • PUMP1
  • PUMP-1
  • uterine matrilysin
  • Uterine metalloproteinase

Background

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for MMP-7 (DMP700)(27)

We have publications tested in 2 confirmed species: Human, Rabbit.


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Human
(24)
Rabbit
(1)
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Showing Publications 1 - 10 of 27. Show All 27 Publications.
Publications using DMP700 Applications Species
F Fang, W Luo, M Yang, P Yang, X Yang Urinary Matrix Metalloproteinase-7 and Prediction of AKI Progression Post Cardiac Surgery Dis. Markers, 2019;2019(0):9217571. 2019 [PMID: 31827648] (Human) Human
I Buendia-Ro, N Machuca, M Mejía, M Maldonado, A Pardo, M Selman Lower levels of α-Klotho in serum are associated with decreased lung function in individuals with interstitial lung abnormalities Sci Rep, 2019;9(1):10801. 2019 [PMID: 31346213] (Human) Human
JN Justice, AM Nambiar, T Tchkonia, NK LeBrasseur, R Pascual, SK Hashmi, L Prata, MM Masternak, SB Kritchevsk, N Musi, JL Kirkland Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study EBioMedicine, 2019;0(0):. 2019 [PMID: 30616998] (Human) Human
J Zhang, P Ren, Y Wang, S Feng, C Wang, X Shen, C Weng, X Lang, Z Chen, H Jiang, J Chen Serum Matrix Metalloproteinase-7 Level is Associated with Fibrosis and Renal Survival in Patients with IgA Nephropathy Kidney Blood Press. Res., 2017;42(3):541-552. 2017 [PMID: 28922659] (Human) Human
FA Piedra, M Mei, V Avadhanula, R Mehta, L Aideyan, RP Garofalo, PA Piedra The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-associated bronchiolitis PLoS ONE, 2017;12(3):e0172953. 2017 [PMID: 28267794] (Human) Human
Anna Lundmark Mucin 4 and matrix metalloproteinase 7 as novel salivary biomarkers for periodontitis J. Clin. Periodontol, 2016;0(0):. 2016 [PMID: 28005264] (Human) Human
Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease J. Cell. Mol. Med, 2016;0(0):. 2016 [PMID: 28004483] (Human) Human
Chen, Chang-Ha, Chang, Alice Y, Li, Shau-Hsu, Tsai, Hsin-Tin, Shiu, Li-Yen, Su, Li-Jen, Wang, Wen-Lung, Chiu, Tai-Jen, Luo, Sheng-De, Huang, Tai-Lin, Chien, Chih-Yen Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer. Mol Cancer, 2015;14(0):83. 2015 [PMID: 25889801] (Human) Human
Chen I, Chiang W, Huang H, Chen P, Shen Y, Chiang H Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis. Mol Cancer, 2014;13(0):254. 2014 [PMID: 25424420] (Human) Human
Keeratichamroen S, Leelawat K, Thongtawee T Expression of CD24 in cholangiocarcinoma cells is associated with disease progression and reduced patient survival. Int. J. Oncol., 2011;39(4):873-81. 2011 [PMID: 21687942]
Show All 27 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for MMP-7 (DMP700). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DMP700
HRP DMP700
HRP DMP700

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Bioinformatics Tool for MMP-7 (DMP700)

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Blogs on MMP-7.

Toll-like receptors in the intestinal epithelial cells
By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria...  Read full blog post.

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Bioinformatics

Gene Symbol MMP7