Human Total MMP-7 Quantikine ELISA Kit



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Reactivity HuSpecies Glossary
Applications ELISA

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Human Total MMP-7 Quantikine ELISA Kit Summary

The Quantikine Human MMP-7 Immunoassay is a 4.5 hour solid phase ELISA designed to measure MMP-7 in cell culture supernates, serum, plasma, saliva, and urine. It contains NS0-expressed recombinant human MMP-7 and antibodies raised against the recombinant factor. The Quantikine kit detected both pro- and active forms of recombinant human MMP-7. Natural human MMP-7 showed dose-response curves ...that were parallel to the standard curves obtained using the kit standards, indicating that this kit can be used to determine relative levels of natural human MMP-7.
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Natural and recombinant human MMP-7
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DMP700.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Total MMP-7 Quantikine ELISA Kit

  • EC 3.4.24
  • EC
  • Matrilysin
  • matrin
  • matrix metallopeptidase 7 (matrilysin, uterine)
  • matrix metalloproteinase 7 (matrilysin, uterine)
  • Matrix metalloproteinase-7
  • MMP7
  • MMP-7
  • MPSL1
  • Pump-1 protease
  • PUMP1
  • PUMP-1
  • uterine matrilysin
  • Uterine metalloproteinase


The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for MMP-7 (DMP700)(37)

We have publications tested in 2 confirmed species: Human, Rabbit.

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Showing Publications 1 - 10 of 37. Show All 37 Publications.
Publications using DMP700 Applications Species
Canela, VH;Bowen, WS;Ferreira, RM;Syed, F;Lingeman, JE;Sabo, AR;Barwinska, D;Winfree, S;Lake, BB;Cheng, YH;Gaut, JP;Ferkowicz, M;LaFavers, KA;Zhang, K;Coe, FL;Worcester, E;Kidney Precision Medicine Project, ;Jain, S;Eadon, MT;Williams, JC;El-Achkar, TM; A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease Nature communications 2023-07-19 [PMID: 37468493] (Human) Human
Kubik, A;das Virgens, IPA;Szab�, A;V�radi, M;Csizmarik, A;Keszthelyi, A;Majoros, A;Feh�rv�ri, P;Hegyi, P;�cs, N;Nyir�dy, P;Szarvas, T; Comprehensive Analysis of the Prognostic Value of Circulating MMP-7 Levels in Urothelial Carcinoma: A Combined Cohort Analysis, Systematic Review, and Meta-Analysis International journal of molecular sciences 2023-04-26 [PMID: 37175566] (Human) Human
A Bahabayi, N Yang, T Xu, Y Xue, L Ma, X Gu, Y Wang, K Jia Expression of Matrix Metalloproteinase-2,-7,-9 in Serum during Pregnancy in Patients with Pre-Eclampsia: A Prospective Study International Journal of Environmental Research and Public Health, 2022-11-04;19(21):. 2022-11-04 [PMID: 36361378] (Human) Human
Á Széles, PT Kovács, A Csizmarik, M Váradi, P Riesz, T Fazekas, S Váncsa, P Hegyi, C Oláh, S Tschirdewa, C Darr, U Krafft, V Grünwald, B Hadaschik, O Horváth, P Nyirády, T Szarvas High Pretreatment Serum PD-L1 Levels Are Associated with Muscle Invasion and Shorter Survival in Upper Tract Urothelial Carcinoma Biomedicines, 2022-10-13;10(10):. 2022-10-13 [PMID: 36289821] (Human) Human
WM Ciszewski, M Chmielewsk, LA Wozniak, K Sobierajsk Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells Oncogene, 2022-05-29;10(6):. 2022-05-29 [PMID: 35740289] (Human) Human
JJ Zhang, CX Cao, LL Wan, W Zhang, ZJ Liu, JL Wang, Q Guo, H Tang Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway World Journal of Gastroenterology, 2022-05-07;28(17):1781-1797. 2022-05-07 [PMID: 35633908] (Human) Human
L Chavez-Gal, A Ruiz, K Martinez-E, H Aguilar-Du, M Torres, R Falfan-Val, G Pérez-Rubi, M Selman, I Buendia-Ro Circulating Levels of PD-L1, TIM-3 and MMP-7 Are Promising Biomarkers to Differentiate COVID-19 Patients That Require Invasive Mechanical Ventilation Biomolecules, 2022-03-14;12(3):. 2022-03-14 [PMID: 35327637] (Human) Human
PT Kovács, T Mayer, A Csizmarik, M Váradi, C Oláh, Á Széles, S Tschirdewa, U Krafft, B Hadaschik, P Nyirády, P Riesz, T Szarvas Elevated Pre-Treatment Serum MMP-7 Levels Are Associated with the Presence of Metastasis and Poor Survival in Upper Tract Urothelial Carcinoma Biomedicines, 2022-03-17;10(3):. 2022-03-17 [PMID: 35327500] (Human) Human
S Ancona, E Orpianesi, C Bernardell, E Chiaramont, R Chiaramont, S Terraneo, F Di Marco, E Lesma Differential Modulation of Matrix Metalloproteinases-2 and -7 in LAM/TSC Cells Biomedicines, 2021-11-24;9(12):. 2021-11-24 [PMID: 34944575] (Human) Human
TV Tellman, LA Cruz, BJ Grindel, MC Farach-Car Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration International Journal of Molecular Sciences, 2021-03-22;22(6):. 2021-03-22 [PMID: 33809984] (Human) Human
Show All 37 Publications.

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Gene Symbol MMP7