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MMP-3 Products

Antibodies
MMP-3 Antibody - BSA Free
MMP-3 Antibody - BSA Free
NB100-91878
Western Blot MMP-3 Antibody - BSA Free
Immunohistochemistry-Paraffin MMP-3 Antibody - BSA Free
Immunohistochemistry-Paraffin MMP-3 Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NB100-91878AF350
Alexa Fluor 405 NB100-91878AF405
Alexa Fluor 488 NB100-91878AF488
Alexa Fluor 532 NB100-91878AF532
Alexa Fluor 594 NB100-91878AF594
Alexa Fluor 647 NB100-91878AF647
Alexa Fluor 700 NB100-91878AF700
Alexa Fluor 750 NB100-91878AF750
Alexa Fluor Plus 405 NB100-91878AFP405
Alexa Fluor Plus 488 NB100-91878AFP488
Alexa Fluor Plus 555 NB100-91878AFP555
Alexa Fluor Plus 594 NB100-91878AFP594
Alexa Fluor Plus 647 NB100-91878AFP647
Alexa Fluor Plus 680 NB100-91878AFP680
Allophycocyanin NB100-91878APC
Biotin NB100-91878B
CoraFluor 1 NB100-91878CL1
DyLight 350 NB100-91878UV
DyLight 405 NB100-91878V
DyLight 488 NB100-91878G
DyLight 550 NB100-91878R
DyLight 594 NB100-91878DL594
DyLight 650 NB100-91878C
DyLight 680 NB100-91878FR
DyLight 755 NB100-91878IR
FITC NB100-91878F
HRP NB100-91878H
Janelia Fluor 525 NB100-91878JF525
Janelia Fluor 549 NB100-91878JF549
Janelia Fluor 646 NB100-91878JF646
Janelia Fluor 669 NB100-91878JF669
PE NB100-91878PE
PerCP NB100-91878PCP
mFluor Violet 450 SE NB100-91878MFV450
mFluor Violet 500 SE NB100-91878MFV500
mFluor Violet 610 SE NB100-91878MFV610
Formulation Catalog # Availability Price  
BSA Free NB100-91878SS
MMP-3 Antibody [Unconjugated] ...
MMP-3 Antibody [Unconjugated]
AF513
WBC015) and lysate of U-118-MG human glioblastoma/astrocytoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human/Primate MMP-3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF513) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for MMP-3 at approximately 57-60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot MMP-3 Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry MMP-3 Antibody [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry MMP-3 Antibody [Unconjugated]
513-MP) was serially diluted and captured by Goat Anti-Human/Primate MMP‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF513) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human/Primate MMP‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF513) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA MMP-3 Antibody [Unconjugated]
513-MP) was serially diluted and captured by Goat Anti-Human/Primate MMP‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF513) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human/Primate MMP‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF513) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank"> ELISA MMP-3 Antibody [Unconjugated]
Species: Hu, Pm
Applications: WB, IHC, IP, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 AF513U-100UG
Alexa Fluor 405 AF513V-100UG
Alexa Fluor 488 AF513G-100UG
Alexa Fluor 532 AF513X-100UG
Alexa Fluor 594 AF513T-100UG
Alexa Fluor 647 AF513R-100UG
Alexa Fluor 700 AF513N-100UG
Alexa Fluor 750 AF513S-100UG
Alexa Fluor Plus 405 AF513AFP405-100UG
Alexa Fluor Plus 488 AF513AFP488-100UG
Alexa Fluor Plus 555 AF513AFP555-100UG
Alexa Fluor Plus 594 AF513AFP594-100UG
Alexa Fluor Plus 647 AF513AFP647-100UG
Alexa Fluor Plus 680 AF513AFP680-100UG
Biotin BAF513
Formulation Catalog # Availability Price  
Carrier Free AF513-SP
MMP-3 Antibody (50647) [Uncon ...
MMP-3 Antibody (50647) [Unconjugated]
MAB513
WBC015). PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human MMP-3 Monoclonal Antibody (Catalog # MAB513) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for MMP-3 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot MMP-3 Antibody (50647) [Unconjugated]
CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in cancer cells (right panel). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank"> Immunohistochemistry MMP-3 Antibody (50647) [Unconjugated]
NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry MMP-3 Antibody (50647) [Unconjugated]
MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules." class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry MMP-3 Antibody (50647) [Unconjugated]
Species: Hu
Applications: WB, IHC, CyTOF-ready, Flow, ICC/IF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 IC513U-100UG
Alexa Fluor 405 IC513V-100UG
Alexa Fluor 488 IC513G-100UG
Alexa Fluor 594 IC513T-100UG
Alexa Fluor 647 IC513R-100UG
Alexa Fluor 700 IC513N-100UG
Alexa Fluor 750 IC513S-100UG
Alexa Fluor Plus 405 FAB513AFP405-100UG
Alexa Fluor Plus 488 FAB513AFP488-100UG
Alexa Fluor Plus 555 FAB513AFP555-100UG
Alexa Fluor Plus 594 FAB513AFP594-100UG
Alexa Fluor Plus 647 FAB513AFP647-100UG
Alexa Fluor Plus 680 FAB513AFP680-100UG
Formulation Catalog # Availability Price  
Carrier Free MAB513-SP
Carrier Free IC513G-100UG
Carrier Free IC513V-100UG
Carrier Free IC513U-100UG
Carrier Free IC513T-100UG
Carrier Free IC513S-100UG
Carrier Free IC513R-100UG
Carrier Free IC513N-100UG
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We have 34 MMP-3 Antibodies
Antibody Pairs
MMP-3 Antibody Pair [HRP]
MMP-3 Antibody Pair [HRP]
NBP2-79467
Sandwich ELISA MMP-3 Antibody Pair [HRP]
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
HRP NBP2-79467-5Plates
HRP NBP2-79467-15Plates
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We have 1 MMP-3 Antibody Pair
ELISA Kits
Human Total MMP-3 Quantikine ...
Human Total MMP-3 Quantikine ELISA...
DMP300
N/A MMP-3 [HRP]
N/A MMP-3 [HRP]
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
HRP PDMP300
HRP SMP300
Human Total MMP-3 DuoSet ELIS ...
Human Total MMP-3 DuoSet ELISA, 15...
DY513
N/A MMP-3 [Biotin]
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Biotin DY513-05
Mouse Total MMP-3 Quantikine ...
Mouse Total MMP-3 Quantikine ELISA...
MMP300
N/A MMP-3 [HRP]
N/A MMP-3 [HRP]
Species: Mu
Applications: ELISA
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We have 14 MMP-3 ELISA Kits
Lysates
MMP-3 Overexpression Lysate
MMP-3 Overexpression Lysate
NBL1-13159
Western Blot MMP-3 Overexpression Lysate
Species: Hu
Applications: WB
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We have 1 MMP-3 Lysate
Proteins
Recombinant Human MMP-3 Prote ...
Recombinant Human MMP-3 Protein, CF
513-MP
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Carrier Free 513-MP-010
Recombinant Human MMP-3 Weste ...
Recombinant Human MMP-3 Western Bl...
WBC015
Species: Hu
Applications: WB
Recombinant Mouse MMP-3 Prote ...
Recombinant Mouse MMP-3 Protein, CF
548-MM
Species: Mu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Carrier Free 548-MM-010
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We have 5 MMP-3 Proteins

Description

Effective inhibitors of matrix metalloproteinases (MMPs), a family of connective tissue-degrading enzymes, could be useful for the treatment of diseases such as cancer, multiple sclerosis, and arthritis (1). Matrix metalloproteinase-3 (MMP-3) is a protein involved in tumor invasion and metastasis. MMP3 (stromelysin) is a secreted metalloprotease with a wide range of substrate specificities. MMP3 is synthesized in a preproenzyme form with a calculated size of 54 kDa and a 17-amino acid long signal peptide. Data indicate that the expression and the possible involvement of secreted metalloproteases in tumorigenesis result from a specific interaction between the transforming factor and the target cell, which may vary in different species (2). In neural studies, matrix metalloproteinase-3 (MMP-3) was newly induced and activated in stressed dopamine cells, and the active form of MMP-3 (actMMP-3) was released into the medium. The released actMMP-3, as well as catalytically active recombinant MMP-3 (cMMP-3) led to microglial activation and superoxide generation in microglia and enhanced DA cell death. (3).

Bioinformatics

Entrez
171045
Rat
17392
Mouse
4314
Human
Uniprot
NM_002422
Human
NP_002413
Human
NP_002413.1
Human
P08254
Human
Product By Gene ID 4314
Alternate Names
  • CHDS6
  • EC 3.4.24
  • EC 3.4.24.17
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • matrix metalloproteinase 3 (stromelysin 1, progelatinase)
  • Matrix metalloproteinase-3
  • MGC126102
  • MGC126103
  • MMP-3
  • proteoglycanase
  • SL-1
  • STMY
  • STMY1MGC126104
  • STR1
  • stromelysin-1
  • Transin-1
  • transin-1

Research Areas for MMP-3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Extracellular Matrix

Related MMP-3 Blog Posts

Check out the latest blog posts on MMP-3.
MMP3 - a potential target for arthritis therapies
Matrix metalloproteinases (MMPs) are responsible for the degradation of extracellular matrix proteins. MMPs are essential for tissue remodeling during normal processes such as embryonic development as well as pathological conditions such as arthri...    Read more.
Read more MMP-3 related blogs.