MMP-3 Products

Antibodies
MMP-3 Antibody
MMP-3 Antibody
NB100-91878
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
MMP-3 Antibody [Unconjugated] ...
MMP-3 Antibody [Unconjugated]
AF513
Species: Hu, Pm
Applications: WB, IHC, IP, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
MMP-3 Antibody (50647) [Uncon ...
MMP-3 Antibody (50647) [Unconjugated]
MAB513
Species: Hu
Applications: WB, IHC, CyTOF-ready, ICC, ICFlow
Host: Mouse Monoclonal
Antibody Pairs
MMP-3 Antibody Pair
MMP-3 Antibody Pair
H00004314-AP11
Species: Hu
Applications: S-ELISA
MMP-3 Antibody Pair
MMP-3 Antibody Pair
H00004314-PW1
Species: Hu
Applications: WB, IP
MMP-3 Antibody Pair
MMP-3 Antibody Pair
H00004314-PW2
Species: Hu
Applications: WB, IP
ELISA Kits
Human MMP-3 ELISA Kit
Human MMP-3 ELISA Kit
KA0394
Species: Hu
Applications: ELISA
Mouse MMP-3 ELISA Kit (Colori ...
Mouse MMP-3 ELISA Kit (Colorimetric)
KA1807
Species: Mu
Applications: ELISA
Lysates
MMP-3 Overexpression Lysate ( ...
MMP-3 Overexpression Lysate (Denat...
H00004314-T01
Species: Hu
Applications: WB
MMP-3 Overexpression Lysate ( ...
MMP-3 Overexpression Lysate (Native)
NBL1-13159
Applications: WB
Proteins
Recombinant Human MMP-3 Prote ...
Recombinant Human MMP-3 Protein, CF
513-MP
Species: Hu
Applications: EnzAct
Recombinant Human MMP-3 Weste ...
Recombinant Human MMP-3 Western Bl...
WBC015
Species: Hu
Applications: WB
Recombinant Mouse MMP-3 Prote ...
Recombinant Mouse MMP-3 Protein, CF
548-MM
Species: Mu
Applications: EnzAct
RNAi
MMP-3 RNAi
MMP-3 RNAi
H00004314-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Effective inhibitors of matrix metalloproteinases (MMPs), a family of connective tissue-degrading enzymes, could be useful for the treatment of diseases such as cancer, multiple sclerosis, and arthritis (1). Matrix metalloproteinase-3 (MMP-3) is a protein involved in tumor invasion and metastasis. MMP3 (stromelysin) is a secreted metalloprotease with a wide range of substrate specificities. MMP3 is synthesized in a preproenzyme form with a calculated size of 54 kDa and a 17-amino acid long signal peptide. Data indicate that the expression and the possible involvement of secreted metalloproteases in tumorigenesis result from a specific interaction between the transforming factor and the target cell, which may vary in different species (2). In neural studies, matrix metalloproteinase-3 (MMP-3) was newly induced and activated in stressed dopamine cells, and the active form of MMP-3 (actMMP-3) was released into the medium. The released actMMP-3, as well as catalytically active recombinant MMP-3 (cMMP-3) led to microglial activation and superoxide generation in microglia and enhanced DA cell death. (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 4314
Alternate Names
  • EC 3.4.24
  • MGC126102
  • Transin-1
  • CHDS6
  • transin-1
  • EC 3.4.24.17
  • stromelysin-1
  • SL-1
  • proteoglycanase
  • MMP-3
  • STR1
  • Matrix metalloproteinase-3
  • STMY
  • matrix metalloproteinase 3 (stromelysin 1, progelatinase)
  • STMY1MGC126104
  • MGC126103
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Research Areas for MMP-3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Extracellular Matrix

Bioinformatics Tool for MMP-3

Discover related pathways, diseases and genes to MMP-3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related MMP-3 Blog Posts

Check out the latest blog posts on MMP-3.
MMP3 - a potential target for arthritis therapies
Matrix metalloproteinases (MMPs) are responsible for the degradation of extracellular matrix proteins. MMPs are essential for tissue remodeling during normal processes such as embryonic development as well as pathological conditions such as arthri...    Read more.
Read more MMP-3 related blogs.